Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles.

By Yongmei Xu, Yumin Du. International journal of pharmaceutics, 2003

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Immunological properties of engineered nanomaterials (2007, background): “Protein binding to the surface of nanoparticles depends on particle surface characteristic”
Antibacterial activity of chitosan tripolyphosphate nanoparticles loaded with various metal ions (2009, methodology): “Chitosan tripolyphosphate nanoparticles have been synthesized and mainly used as drug carrier as reported in previous studies (De Campos, Sánchez, & Alonso, 2001; Janes, Fresneau, Marazuela, Fabra, & Alonso, 2001; Xu & Du, 2003).”
Chitosan—A versatile semi-synthetic polymer in biomedical applications (2011, neutral): “duced by the ionic gelation of TPP and chitosan were studied by Xu and Du [141].”
Hydrogel nanoparticles in drug delivery. (2008, background): “[177] have studied different formulations of chitosan NPs”
Nanoencapsulation of Zataria multiflora essential oil preparation and characterization with enhanced antifungal activity for controlling Botrytis cinerea, the causal agent of gray mould disease (2015, background): “…of the surrounding CS with TPP. CS in acidic media (pKa 6.5) has amino groups that can undergo protonation and interact with the negatively charged TPP, forming inter- and intramolecular cross-linkages, yielding ionically cross-linked CSNPs (De Campos, Sánchez, & Alonso, 2001; Xu & Du, 2003).”