Immunological properties of engineered nanomaterials

By M. Dobrovolskaia, S. McNeil. Nature Nanotechnology, 2007

1,750 citations recorded by the source corpus.

Subfields: Biomaterials, Immunology, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/157570e4c7afd7e9b6d4085e7fe8ec40adef7b76

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Citations in the corpus

Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles. (2009, background): “Nanoparticles could also be identified as foreign by the immune cells, causing the cells to react against either surface or core components to mount an inflammatory response, which involves secretion of signaling molecules (known as cytokines) to attract more cells to destroy the foreign substances ”
Enzyme-responsive nanoparticles for drug release and diagnostics. (2012, background): “Although noble metals such as gold have relatively low reactivity and excellent corrosion resistance, the utilization of metallic nanoparticles for in vivo applications has raised serious toxicological concerns [51, 24–26].”
Protein-Nanoparticle Interactions (2013, background): “The electrocatalytic properties of these electrodes can be further improved by incorporating metal nanoparticles [35], furthering neuroscience research on nerve stimulation [36], acute pain [37], and implantable drug-delivery systems [38].”
Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods. (2010, background): “This is largely due to the lack of an effective paradigm for comprehensively evaluating these related properties [29,30].”
The journey of a drug-carrier in the body: an anatomo-physiological perspective. (2012, background): “CDC retention in the spleen is usually undesired because it can lead to immunogenic reactions (see the accelerated blood clearance (ABC) phenomenon described below) [79].”
Understanding biophysicochemical interactions at the nano-bio interface. (2009, background): “For particle phagocytosis (the active engulfment of particulates by professional phagocytes, including macrophages and dendritic cell”
Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications. (2010, background): “Understanding the targeting of nanoparticles and their cargo to antigen-presenting cells is an important challenge especially for immuno-modulatory applications such as nanovaccine development [132].”
Magnetic nanoparticles for theragnostics (2009, background): “, albumin, apolipoprotein, immunoglobulins, complement, fibrinogen), which promotes their recognition and clearance by cells of RES [25,55].”