Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly

By K. Tolias, J. H. Hartwig, H. Ishihara, Y. Shibasaki, Lewis C. Cantley, Christopher L. Carpenter. 2000

241 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8d211627e80d55720abca10a2bbca6747333bc57

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. A. Ridley

In Immunology and Allergy

1. A. Ridley

In Molecular Biology

1. A. Ridley
2. Alan Hall
3. A. Jaffe

Citations in the corpus

• Rho GTPases: biochemistry and biology. (2005, background): “Many are involved in lipid metabolism and some have been implicated in GTPasemediated changes to the actin cytoskeleton (Tolias et al. 2000, Wang et al. 2002).”
• Rho GTPases and cell migration. (2001, background): “In platelets, Rac acts via a phosphatidylinositide 4-phosphate 5-kinase (PIP 5-kinase) to induce the formation of PtdIns(4,5)P2, which then binds to capping proteins and removes them from the barbed ends of actin filaments (Carpenter et al., 1999; Tolias et al., 2000).”
• Shaping cups into phagosomes and macropinosomes (2008, unknown): “, but also by activating PtdIns4P 5-kinase (PI5K) and PAK1 (Ref”