Mitochondria and reactive oxygen species.

By F. Addabbo, M. Montagnani, M. Goligorsky. HYPERTENSION, 2009

641 citations recorded by the source corpus.

Subfields: Molecular Biology, Pathology and Forensic Medicine, Physiology

View Paper: https://www.semanticscholar.org/paper/8b0d0958f3ed326ac09fd17398589e166291c95b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Pathology and Forensic Medicine

F. B. Hu

In Physiology

Citations in the corpus

Mitochondria-Ros Crosstalk in the Control of Cell Death and Aging (2011, background): “Because of this, succinate may promote ROS generation at Complex I level [6, 7].”
Mitochondrial dysfunction and oxidative stress in metabolic disorders - A Step towards mitochondria based therapeutic strategies (2016, background): “Also, recent studies have indicated abnormal mitochondrial dynamics along with overproduction of ROS in diabetic patients [93,120].”
Endothelial dysfunction - a major mediator of diabetic vascular disease. (2013, background): “fibrinolytic ability, enhanced turnover, overproduction of growth factors, increased expression of adhesion molecules and inflammatory genes, excessive generation of ROS, increased oxidative stress, and enhanced permeability of the cell layer [54-58].”
Mitochondrial electron transport chain, ROS generation and uncoupling (Review) (2019, background): “The occurrence of numerous diseases and hypoxia are closely related to the increase of ROS production. cI and cIII, especially cI, are considered to be the main sites of ROS production in mitochondria (51,52).”
Fructose and Sugar: A Major Mediator of Nonalcoholic Fatty Liver Disease (2018, positive): “aconitase-2 (in the Kreb cycle) and enoyl CoA hydratase (involved in b-fatty acid oxidation).(106,107) Fructose and uric acid have been shown to reduce aconitase-2 activity, leading to”
Factors enhancing fish sperm quality and emerging tools for sperm analysis (2014, background): “In the majority of eukaryotic cell types, mitochondrial energy metabolism is the most important source of ROS (Kowaltowski et al., 2009).”
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? (2010, background): “ROS generation is frequently accompanied by K + efflu”
Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases. (2014, background): “Electron leakage from MRC complexes I and III results in reduction of molecular oxygen, thus forming O2 · (157).”