Default network connectivity reflects the level of consciousness in non-communicative brain-damaged patients.

By Audrey Vanhaudenhuyse, Quentin Noirhomme, L. Tshibanda, Marie-Aurélie Bruno, Pierre Boveroux, C. Schnakers, A. Soddu, Vincent Perlbarg, D. Ledoux, Jean-François Brichant and 5 more. Brain : a journal of neurology, 2010

840 citations recorded by the source corpus.

Subfields: Atomic and Molecular Physics, and Optics, Cognitive Neuroscience, Epidemiology

View Paper: https://www.semanticscholar.org/paper/89a6ef30c38ea03bcee01e3ba7026070595326dd

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In Atomic and Molecular Physics, and Optics

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Steven Laureys

Citations in the corpus

Resting state fMRI: A review of methods and clinical applications (2012, background): “a negative correlation between the connectivity of the DMN and the level of consciousness impairment.(74) Pattern classifi-”
EEG correlates of time-varying BOLD functional connectivity (2013, neutral): “(Horovitz et al., 2009; Samann et al., 2011; Vanhaudenhuyse et al., 2010) as well as on finer-grained temporal scales (seconds to minutes) within the duration of a typical resting state scan.”
The Human Connectome Project and Beyond: Initial Applications of 300 mT/m Gradients (2013, background): “…techniques have begun to identify the neural networks in the cerebral hemispheres that enable recovery of awareness (Fernandez-Espejo et al., 2012; Vanhaudenhuyse et al., 2010), but the pathways in the brainstem ascending reticular activating system (ARAS) that facilitate recovery of arousal…”
A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior (2013, methodology): “The second category includes methods that evaluate the spatial extent or synchronization of brain activations, such as late event–related potentials (32), measures of effective connectivity derived from dynamic causal modeling analysis (33) or from TMS/EEG data (24, 34), and Granger causality and co”
Resting‐state networks show dynamic functional connectivity in awake humans and anesthetized macaques (2013, background): “Changes in connectivity have been reported within and across both normal and disease states [Greicius, 2008; Horovitz et al., 2009; Vanhaudenhuyse et al., 2010].”
Breakdown of within- and between-network Resting State Functional Magnetic Resonance Imaging Connectivity during Propofol-induced Loss of Consciousness (2010, background): “These results are in line with reports of impaired thalamocortical connectivity in default network in vegetative state.(43,46) During unconsciousness, the thalamus became anticorrelated with default network and executive-control networks cortical networks activity (fig.”
Dynamic functional connectivity of the default mode network tracks daydreaming (2014, background): “However, network FC strength may vary for different cognitive states (Shirer et al., 2012) and consciousness levels (Vanhaudenhuyse et al., 2010).”
The role of the posterior cingulate cortex in cognition and disease. (2014, background): “PCC metabolism and connectivity is also low in the vegetative state and increases as patients regain consciousness (Laureys et al., 1999, 2000; Vanhaudenhuyse et al., 2010; Heine et al., 2012).”