A Theoretically Based Index of Consciousness Independent of Sensory Processing and Behavior

By Adenauer G. Casali, Olivia Gosseries, Mario Rosanova, Melanie Boly, Simone Sarasso, K. Casali, Silvia Casarotto, Marie-Aurélie Bruno, Steven Laureys, Giulio Tononi and 1 more. Science Translational Medicine, 2013

1,138 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/8712d449aca179c98f605231af2e13ef2df2a2d4

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In Cognitive Neuroscience

Citations in the corpus

The spectral exponent of the resting EEG indexes the presence of consciousness during unresponsiveness induced by propofol, xenon, and ketamine (2019, neutral): “PCI is based upon the evoked EEG response to 135 transcranial magnetic stimulation (TMS), and represents another marker of consciousness independent of 136 sensory processing and behavioural responsiveness [43,44].”
Signature of consciousness in the dynamics of resting-state brain activity (2015, methodology): “An important consequence of the present results, which should be tested in future research, is that the temporal dynamics of spontaneous brain activity, measured using the entropy of the state transition matrix, might supplement existing tools (18, 19, 42) as a clinically useful index of consciousne”
How can we measure awareness? An overview of current methods (2015, background): “How can I objectively have access to what another person thinks or experiences? Can a person him-/herself objectively assess or report what he/she thinks? Does introspection afford privileged access, or is it merely glorified heterophenomenology? And even if introspection were truly reliable, do int”
Why fish do not feel pain (2016, positive): “These quantitative values have been successfully used to distinguish between conscious, minimally-conscious and nonconscious patients (Casali et al., 2013; King et al., 2013; Sitt et al., 2014).”
From the Phenomenology to the Mechanisms of Consciousness: Integrated Information Theory 3.0 (2014, background): “Under such conditions, consciousness invariably fades [14].”
TMS and drugs revisited 2014. (2015, background): “Notably, PCI in patients with a stable clinical diagnosis of VS was as low as in NREM sleep and anesthesia, but was invariably higher in subjects who regained consciousness, including MCS, EMCS and locked-in syndrome patients (Casali et al., 2013).”
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans (2025, unknown): “Likewise, perturbational approaches that combine transcranial magnetic stimulation (TMS) and EEG [162,163], which are highly sensitive to detecting consciousness even in the presence of strong delta activity [164,165], may provide further insights.”
Separating Neural Oscillations from Aperiodic 1/f Activity: Challenges and Recommendations (2021, background): “The perturbational complexity index (Casali et al., 2013) follows these lines to separate unconscious states of low excitability (non-REM sleep, anesthesia) from conscious states of high excitability (wakefulness, REM sleep).”