Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity.

By C. Bogdan, M. Röllinghoff, A. Diefenbach. Current Opinion in Immunology, 2000

980 citations recorded by the source corpus.

Subfields: Biochemistry, Immunology, Physiology

View Paper: https://www.semanticscholar.org/paper/88807a67da7c71e7c5f287289307526004756af0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. David B. Graves
2. Kelsey H. Fisher-Wellman
3. C. Bogdan
4. R. Bloomer

In Immunology

1. M. Strand
2. T. Mempel
3. David B. Graves
4. C. Bogdan
5. B. Lee
6. Ulrich H. von Andrian
7. VJ Marmaras
8. S. Tsakas

In Physiology

1. David B. Graves
2. C. Bogdan

Citations in the corpus

• The emerging role of reactive oxygen and nitrogen species in redox biology and some implications for plasma applications to medicine and biology (2012, background): “The purpose of the immune system is to recognize pathogenic organisms (distinguishing ‘self’ from ‘non-self’) and clear infections and tumours [28, 79].”
• Recent advances in the innate immunity of invertebrate animals. (2005, background): “In addition to these enzyme cascades, a variety of agglutinin-lectins and reactive oxygenproducing and phagocytic systems cooperate with immune reactions to kill invading pathogens (Bogdan et al., 2000).”
• Insect immunity and its signalling: an overview (2010, background): “In addition, humoral immune responses include activation of enzymic cascades that regulate coagulation and melanization of hemolymph, and production of reactive oxygen and nitrogen species (ROS-RNS) (Gilespie et al., 1997; Bogdan et al., 2000; Nappi and Vass, 2001; Hoffmann, 2003; Mavrouli et al., 2”
• Homing and cellular traffic in lymph nodes (2003, background): “However, supraphysiological oxygen concentrations enhance oxidative stress in living tissues and by shifting redox balances might alter lymphocyte behaviou”
• Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases (2011, neutral): “First, the amino terminal residues [1–95] contain an N-linked glycosylation site at Asn-89, which is useful in the separation of SOD3 from cytosolic SOD1 and greatly increases the solubility of the protein (56).”
• Nitric oxide and the immune response (2001, background): “The analysis of iNOS −/− mice unequivocally demonstrates that most of these effects are mediated by iNOS-derived N”
• Insect hemocytes and their role in immunity. (2002, background): “, 2000; Lowenberger, 2001), reactive intermediates of oxygen or nitrogen (Bogdan et al., 2000; Vass and Nappi, 2001), and the complex enzymatic cascades that regulate coagulation or melanization of hemolymph (Muta and Iwanaga, 1996; Gillespie et al.”
• A review of the interaction among dietary antioxidants and reactive oxygen species. (2007, background): “Innate immunity During the initial response to an invading pathogen, activation of the innate immune response, characterized by generation of ROS within phagocytic cells such as macrophages and neutrophils, is a critical event in the initiation of phagocytosis and subsequent destruction of these mic”