The C. elegans TGF-β Dauer Pathway Regulates Longevity via Insulin Signaling

By W. M. Shaw, Shijing Luo, Jess N. Landis, Jasmine M. Ashraf, Coleen T. Murphy. 2007

217 citations recorded by the source corpus.

Subfields: Aging, Molecular Biology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/86b034dc376bdc2a4a99a88ece9f508c886ea988

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Aging

1. A. Brunet
2. C. Kenyon
3. David M. Sabatini
4. Hilmar Bading
5. G. Hardingham
6. R. DePinho
7. Ergun Sahin

In Molecular Biology

1. Dervis A M Salih
2. C. Kenyon
3. Noah Ollikainen
4. A. Brunet
5. Hilmar Bading
6. G. Hardingham

Citations in the corpus

• FoxO transcription factors in the maintenance of cellular homeostasis during aging. (2008, background): “For example, the growth-inhibitory cytokine transforming growth factor-b (TGFb) triggers the formation of a complex between FoxO, Smad, and C/EBPb transcription factors at specific promoters, which results in the expression of cell cycle inhibitor genes, including p15 and p21 [30,33 ,34 ,39,40].”
• Widespread Protein Aggregation as an Inherent Part of Aging in C. elegans (2010, background): “Found at: doi:10.1371/journal.pbio.1000450.s010 (0.07 MB XLS) Table S3 Age-dependent aggregation-prone proteins identified as significantly regulated in daf-2(e1370) versus daf-16(mu86); daf-2(e1370) microarrays (Shaw et al. 2007 [47]).”