MicroRNA genes are transcribed by RNA polymerase II

By Yoontae Lee, Minju Kim, Jinju Han, Kyu‐Hyun Yeom, Sanghyuk Lee, S. H. Baek, V. Narry Kim. EMBO Journal, 2004

4,597 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/8676f2e981a6e8e94e1302c9869c71aaeb99fd9d

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Citations in the corpus

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. (2006, background): “MiRNA biogenesis is initiated via transcription by RNA polymerase II (Cai et al., 2004; Kim, 2005a; Lee et al., 2002, 2004 ).”
miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis (2020, background): “Biogenesis of miRNA begins in the nucleus, where the transcription of its precursor, primary miRNA or pri-miRNA takes place under the influence of RNA polymerases II and III [11,12].”
Biogenesis of small RNAs in animals (2009, background): “The transcription of most miRNA genes is mediated by RNA polymerase II (Pol II”
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. (2008, background): “Primary miRNA transcripts (pri-miR) are transcribed by RNA Polymerase II (2) and may be derived either from their own dedicated transcripts, or from within the transcripts of known protein-coding genes.”
MicroRNA: Biogenesis, Function and Role in Cancer (2010, background): “(2004) indicates that the majority of miRNA are transcribed by RNA polymerase II (pol II) [38, 42-44].”
Bioinformatic discovery of microRNA precursors from human ESTs and introns (2006, background): “Lee and colleagues presented the first direct evidence that miRNA genes can be transcribed by RNA polymerase II [10].”
MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review (2012, neutral): “Furthermore, most miRNAs are known to be downstream Pol II promoters, within known protein coding genes and expressed by Pol II activity (Lee et al, 2004).”
microRNAs in cancer (2013, background): “First, miRNA genes are transcribed into primary capped and polyadenylated precursors of miRNA (pri-miRNAs) by Pol II (8).”
The Drosha-DGCR8 complex in primary microRNA processing. (2004, background): “Although Dicer associates with several other proteins (Argonaute proteins in various organisms, RDE-4 in Caenorhabditis elegans, R2D2 in Drosophila, and dFMR1 in Drosophila) (Hammond et al. 2001; Ishizuka et al. 2002; Tabara et al. 2002; Liu et al. 2003), these interacting proteins do not seem to be”