Tumor necrosis factor-alpha mediates one component of competitive, experience-dependent plasticity in developing visual cortex.

By Megumi Kaneko, D. Stellwagen, R. Malenka, Michael P. Stryker. 2008

383 citations recorded by the source corpus.

Subfields: Cell Biology, Cellular and Molecular Neuroscience, Neurology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

In Cellular and Molecular Neuroscience

In Neurology

Citations in the corpus

Modeling the dynamic interaction of Hebbian and homeostatic plasticity. (2014, methodology): “In simulations of binocular cortex, ei =C, i = 1 : 310; ei = I, i = 311 : 500, which reproduces the experimentally observedODI of about 0.25 under normal vision (Kaneko et al., 2008b).”
Removing brakes on adult brain plasticity: from molecular to behavioral interventions (2010, positive): “…recalibrated by homeostatic processes (Pozo and Goda, 2010), involving cell-intrinsic transcription factors (Greer and Greenberg, 2008; Chang et al., 2010) or surrounding gliaderived factors such as tumor necrosis factor or the complement cascade (Stevens et al., 2007; Kaneko et al., 2008).”
Microglia: new roles for the synaptic stripper. (2013, positive): “In mice deficient in TNF-a the increase in response to the open eye is absent, thereby suggesting an experience- and TNF-a-dependent mechanism (Kaneko et al., 2008).”
The Self-Tuning Neuron: Synaptic Scaling of Excitatory Synapses (2008, positive): “Visual cortical microcircuitry can be modified in an activity-dependent manner in response to changes in sensory experience (Katz and Shatz, 1996), and there is now mounting evidence that synaptic scaling plays important roles during various critical periods of visual system development.”
Immune modulation of learning, memory, neural plasticity and neurogenesis. (2011, background): “…such as homeostatic synaptic scaling following prolonged inhibition of neuronal activity, via secretion of the pro-inflammatory cytokine TNFa (Kaneko et al., 2008; Stellwagen and Malenka, 2006), a known synaptic strength enhancer, which increases the surface expression of AMPA glutamatergic…”
The mystery and magic of glia: a perspective on their roles in health and disease. (2008, background): “TNFa even plays a role in controlling normal function and plasticity of neural circuits in vitro and in vivo (Stellwagen and Malenka, 2006; Kaneko et al., 2008).”
Synaptic scaling and homeostatic plasticity in the mouse visual cortex in vivo. (2013, background): “…(Desai et al., 2002; Goel et al., 2006; Goel and Lee, 2007; Maffei and Turrigiano, 2008; Gao et al., 2010; Lambo and Turrigiano, 2013), and evoked responses have been shown to increase in vivo during the critical period after long-term deprivation (Mrsic-Flogel et al., 2007; Kaneko et al., 2008).”
Firing Rate Homeostasis in Visual Cortex of Freely Behaving Rodents (2013, background): “…far been definitive; in vivo calcium or intrinsic signal imaging in anesthetized animals revealed that MD first reduced and then increased visual drive (Mrsic-Flogel et al., 2007; Kaneko et al., 2008), but average visual drive was not well conserved during this process (Mrsic-Flogel et al., 2007).”
Synaptic Mechanisms for Plasticity in Neocortex (2009, background): “However, response depression can also occur when all inputs are deprived (Wallace & Fox 1999, Kaneko et al. 2008b), which is more consistent with noncompetitive, homosynaptic plasticity driven by residual activity on deprived pathways (Rittenhouse et al. 1999, Frenkel & Bear 2004).”
Homeostatic synaptic plasticity: local and global mechanisms for stabilizing neuronal function. (2012, background): “Interestingly, the delayed potentiation in visual cortex following lid suture requires TNFa and Arc signaling (Kaneko et al. 2008; McCurry et al. 2011) as does synaptic scaling in vitro (Shepherd et al. 2006; Stellwagen and Malenka 2006; Steinmetz and Turrigiano 2010); however, both these…”