The branching programme of mouse lung development

By Ross J. Metzger, O. Klein, G. Martin, M. Krasnow. Nature, 2008

768 citations recorded by the source corpus.

Subfields: Physiology, Statistical and Nonlinear Physics

View Paper: https://www.semanticscholar.org/paper/839e15784af2a0074cf7c0c6dcf42b05bb13ed56

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Physiology

1. C. Wright
2. Keith E. Mostov
3. F. C. Pan
4. H. Chapman
5. E. Morrisey
6. David M. Bryant
7. B. Hogan

In Statistical and Nonlinear Physics

1. C. Wright
2. Jeffrey A. Whitsett
3. F. C. Pan
4. E. Morrisey
5. B. Hogan

Citations in the corpus

• Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development (2010, methodology): “During branching morphogenesis the lung buds undergo repetitive cycles of four processes: bud elongation, cessation of outgrowth, expansion of the tip, and bifurcation (either planar or orthogonal) (Metzger et al., 2008).”
• Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development (2010, neutral): “In the lungs, studies of in vivo branching have revealed a highly stereotyped pattern, with specific, genetically encoded branchingmodules that are employed to generate the characteristic shape of the organ (Metzger et al., 2008).”
• Pancreas organogenesis: From bud to plexus to gland (2011, methodology): “High-resolution real-time imaging and detailed in vivo quantitative genetic analysis (similar to that performed for the lung epithelium; Metzger et al., 2008) could provide dramatic discoveries related to the control of endocrine cell birth, and where, for example, b-cell versus other…”
• From cells to organs: building polarized tissue (2008, background): “This design principle can make repeated use of such budding mechanisms, with the branches following simple pattern”
• Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling (2010, background): “branches (intrapulmonary airways), which have a stereotypical branching pattern (Metzger et al., 2008).”
• Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function (2014, background): “The buds extend and branch in a pattern that is initially very stereotypic but becomes less so as development proceeds (Metzger et al., 2008; Morrisey and Hogan, 2010; Short et al., 2013).”