Tensile forces govern germ-layer organization in zebrafish

By Michael Krieg, Y. Arboleda-Estudillo, Pierre-Henri Puech, Jos Käfer, François Graner, D. Müller, Carl-Philipp Heisenberg. Nature Cell Biology, 2008

781 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Ocean Engineering

View Paper: https://www.semanticscholar.org/paper/14de4d81849619a57b0274ae306c077596f9deb7

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Citations in the corpus

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst (2010, background): “It has been shown that cortical tension plays an important role in sorting out different cell populations, in addition to adhesion differences (Krieg et al., 2008).”
Biomechanical remodeling of the microenvironment by stromal Caveolin-1 favors tumor invasion and metastasis (2011, background): “In embryogenesis such tensile forces govern tissue organization (Krieg et al., 2008), and mammary acinar architecture relies on matrix compliance and cell tension (Ronnov-Jessen and Bissell, 2008).”
A tense situation: forcing tumour progression (2009, background): “Force has a fundamental role in directing stem cell fate and in dictating embryonic developmen”
Comparative advantages of mechanical biosensors (2011, methodology): “This has been used to investigate a wide variety of phenomena, from the properties of cell adhesion itsel”
Intrinsic extracellular matrix properties regulate stem cell differentiation. (2010, background): “, 2005), and even such basic principles as germ layer sorting based on mechanics (Krieg et al., 2008).”
Balancing forces: architectural control of mechanotransduction (2011, positive): “The level of cortical tension (stiffness, as measured by atomic force microscopy) is different in cells that make up the zebrafish ectoderm, mesoderm and endoder”
Mechanical control of tissue and organ development (2010, methodology): “It can also be used to determine the force required to deform ECM-integrin adhesions (Choquet et al., 1997), to physically separate adherent single cells (Krieg et al., 2008), or to stretch single molecules (Puchner et al., 2008).”
The myofibroblast: paradigm for a mechanically active cell. (2010, background): “MA, a-smooth muscle actin; , focal adhesion; FN, ent transforming growth anscription factor; TGFb, of cell fate (Krieg et al., 2008).”
Mechanotransduction in development: a growing role for contractility (2009, background): “Krieg has recently revisited this phenomenon in zebrafish and found that differences in actomyosin-dependent cell-cortex tension, and not only differences in adhesion, are necessary and sufficient for progenitor sortin”
Cell mechanics and the cytoskeleton (2010, positive): “As one example, in gastrulating zebrafish embryos, actin- and myosin-dependent plasma-membrane tension and differential adhesion among cells drives the sorting of germ-layer progenitor cell”