A Continuum of Anionic Charge: Structures and Functions of d-Alanyl-Teichoic Acids in Gram-Positive Bacteria

By F. C. Neuhaus, J. Baddiley. Microbiology and Molecular Biology Reviews, 2003

1,057 citations recorded by the source corpus.

Subfields: Biochemistry, Genetics, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/8230ba47cf56d18c5e08fcbef00694d65b560e30

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. B. Kruijff
2. E. Breukink
3. A. Peschel
4. W. Nauseef

In Genetics

1. B. Kruijff
2. E. Breukink
3. A. Peschel
4. M. G. Pinho
5. D. Kahne
6. W. Nauseef
7. T. Silhavy
8. D. Scheffers

In Organic Chemistry

1. B. Kruijff
2. E. Breukink
3. A. Peschel
4. W. Nauseef

Citations in the corpus

• Bacterial Cell Wall Synthesis: New Insights from Localization Studies (2005, background): “which are covalently linked to PG (57, 131).”
• Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses (2004, background): “In addition, the hydrophobic surfaces of lipoteichoic acid and peptidoglycan are hidden in aggregate”
• The bacterial cell envelope. (2010, background): “The hydroxyls on the RboP or GroP repeats are tailored with other groups, typically D-alanyl esters or glycosyl moieties, and the nature and extent of the tailoring modifications significantly affect the properties and functions of WTAs (see later) (Neuhaus, 2003).”
• Mechanisms of nisin resistance in Gram-positive bacteria (2013, neutral): “…monocytogenes Palmer et al. 2009 into the mostly negatively charged cell wall (Delcour et al. 1999; Peschel et al. 1999; Mantovani and Russell 2001; Neuhaus and Baddiley 2003), and the increased positive charges in the cell wall probably hamper nisin from reaching lipid II in the cytoplasmic…”
• Wall teichoic acids of gram-positive bacteria. (2013, background): “Wall teichoic acids (WTAs) are the most abundant PG-linked glycopolymers in many gram-positive organisms (91).”
• Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions (2008, background): “One constant motif of Gram-positive cell envelopes, however, is the presence of additional glycopolymers, which form part of the fabric of the cell wall and are attached either to the peptidoglycan or to membrane lipid”
• Lipid II as a target for antibiotics (2006, positive): “This is used by the bacterium to regulate the charge of the cell wall 68 , and it is this regulation of cell-wall charge that seems to be the most important mechanism leading to nisin-resistance.”
• Genes and Molecules of Lactobacilli Supporting Probiotic Action (2008, background): “Additionally, D-Ala esters of LTA and WTA have been suggested to be necessary for the proper functioning of cell integrity at low pH and in the presence of bile (179).”