Analysis of yeast protein kinases using protein chips

By Hengying Zhu, J. Klemic, Swan Chang, Paul Bertone, A. Casamayor, K. Klemic, David Smith, Mark Gerstein, Mark A. Reed, M. Snyder. Nature Genetics, 2000

769 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/80f1a0685d352e6d9fdf6e7d2c07cb0155dcf6ee

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Citations in the corpus

Calcium Signaling through Protein Kinases. The Arabidopsis Calcium-Dependent Protein Kinase Gene Family1 (2002, background): “This approach could be further explored on a genomic scale, using immobilized substrates (proteins or peptides) on microarray surfaces (Zhu et al., 2000).”
Mapping pathways and phenotypes by systematic gene overexpression. (2006, methodology): “Like the pho85D kinase mutant, we predicted CRZ1 overexpression in a mutant lacking the relevant Pho85 cyclin(s) would result in slow growth.”
Protease degradomics: A new challenge for proteomics (2002, background): “For example, protein-kinase chips have been developed to assess the ability of kinases to phosphorylate immobilized substrate”
Phosphorylation of γ-Tubulin Regulates Microtubule Organization in Budding Yeast (2001, background): “The tub4-Y445D mutation has a more pronounced effect on microtubule assembly andgesting that this form of modification is rare (see Zhu et al., 2000; Modesti et al., 2001).”
Subcellular localization of the yeast proteome. (2002, background): “…et al. 2000; Ito et al. 2001; Tong et al. 2002), immunoprecipitation/mass spectrometric analysis of protein complexes (Gavin et al. 2002; Ho et al. 2002), and protein microarray technologies (MacBeath and Schreiber 2000; Zhu et al. 2000, 2001) are yielding unprecedented quantities of protein data.”
Molecular Biologist's Guide to Proteomics (2002, background): “Protein arrays are undergoing rapid development for the detection of protein-protein interactions and protein expression profiling (17, 98, 180, 181).”
Mechanisms of specificity in protein phosphorylation (2007, background): “Considering their broad importance in signal transduction, it is not surprising that protein kinases are one of the largest families of genes in eukaryotes — making up ∼2% of the genome — and have been extensively studie”