Replication of hepatitis C virus.

By Ralf Bartenschlager, V. Lohmann. Journal of General Virology, 2000

1,278 citations recorded by the source corpus.

Subfields: Animal Science and Zoology, Epidemiology, Hepatology

View Paper: https://www.semanticscholar.org/paper/80d3e2aa369550d841c67f7d122882bfaec4b7d7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Animal Science and Zoology

1. T. Balla

In Epidemiology

1. Charles M. Rice
2. T. Balla
3. R. Kaufman
4. Gary R. Whittaker
5. J. Millet
6. S. Belouzard
7. J. Malhotra

In Hepatology

1. Charles M. Rice
2. T. Balla
3. Gary R. Whittaker
4. S. Belouzard
5. J. Millet

Citations in the corpus

• iArc monogrAphs on the evAluAtion oF cArcinogenic risks to humAns (2012, background): “This includes the lipoprotein receptors scavenger receptor B1 (SR-B1), and the low-density lipoprotein receptor (LDLr), which may mediate indirect uptake of HCV via HCV-associated lipoproteins (Moradpour et al., 2007).”
• Phosphoinositides: tiny lipids with giant impact on cell regulation. (2013, background): “viral protein NS5A (13), which by itself can generate membrane structures resembling the “membranous web” (1082).”
• Endoplasmic Reticulum Stress in Liver Disease (2010, background): “Thus, HCV viral replication is intimately linked to the ER [93].”
• Interferon-Stimulated Genes: A Complex Web of Host Defenses (2014, background): “Within these droplets viperin interacts with both the host [vesicle-associated membrane protein–associated protein A (VAP-A, also known as VAP-33)] and the HCV non-structural protein 5A (NS5A), a key protein required for viral replication, assembly, and egress (202).”
• Modification of intracellular membrane structures for virus replication (2008, background): “HCV infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma, and affects 170 million people worldwide 4 .”
• Infectious Hepatitis C Virus Pseudo-particles Containing Functional E1–E2 Envelope Protein Complexes (2003, background): “Our data indicate that the E1 and E2 glycoproteins represent the envelope glycoproteins of wild-type HCV and are both required for infection; each glycoprotein is potentially involved in separate steps of cell entry (9, 17).”