Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y.

By H.A. Bischoff-Ferrari, T. Dietrich, E. Orav, F. B. Hu, Yuqing Zhang, E. Karlson, B. Dawson-Hughes. American Journal of Clinical Nutrition, 2004

1,007 citations recorded by the source corpus.

Subfields: Molecular Biology, Pathology and Forensic Medicine, Physiology

View Paper: https://www.semanticscholar.org/paper/80a95b2b512d10aacb72c98ed7dfe47673b2befb

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Citations in the corpus

Vitamin D physiology. (2006, background): “Muscle function was optimal with a 25(OH)D level higher than 60 nmol/l (Bischoff-Ferrari et al., 2004a).”
Position of the American Dietetic Association, Dietitians of Canada, and the American College of Sports Medicine: Nutrition and athletic performance. (2009, background): “These athletes ould benefit from supplementation ith vitamin D at the Dietary Refernce Intake level (5 g/day or 200 IU or ages 19 to 49 years) (54,56,58-61).”
Vitamin D2 is much less effective than vitamin D3 in humans. (2004, background): “Furthermore, lower extremity muscle function improves across virtually the entire range of prevailing serum 25OHD concentrations (21).”
Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. (2011, background): “00) (116), whereas 400 IU/d was insufficient to”
Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials (2009, background): “(25(OH)D; calcidiol (25-hydroxycholecalciferol)) required to prevent falls in older individuals. Notably, two epidemiology studies among older individuals have found a dose-response relationship between lower extremity function and serum 25(OH)D concentrations,”
Vitamin D—Effects on Skeletal and Extraskeletal Health and the Need for Supplementation (2013, background): “There is a positive association between 25(OH)D, lower extremity function, proximal muscle strength and physical performance [107,121,122].”
Vitamin D for Health: A Global Perspective (2013, positive): “Much of the improvement occurred at 25(OH)D levels ranging from 9 to 16 ng/mL but continued to be seen at levels up to 40 ng/mL.(69) A systematic review revealed that supplemental vitamin D at daily doses of 800 to 1000 IU consistently had beneficial effects on muscle strength and balance.”
High prevalence of vitamin D inadequacy and implications for health. (2006, result): “Similarly, results of a metaanalysis of RCTs suggest that vitamin D can reduce the risk of falls.(143) Many lines of research support the concept that inadequate vitamin D may be involved in the pathogenesis and/ or progression of several disorders, including cancer, hypertension, cardiovascular dis”
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. (2006, background): “Some of the authors of this review therefore evaluated the association between 25(OH)D concentrations and alveolar attachment loss, a measure of periodontal disease, in 11 202 ambulatory subjects aged ͧ20 y in NHANES III (30).”