Regulation of endoplasmic reticulum turnover by selective autophagy

By Aliaksandr Khaminets, Theresa Heinrich, M. Mari, P. Grumati, A. Huebner, M. Akutsu, L. Liebmann, Alexandra Stolz, S. Nietzsche, Nicole Koch and 8 more. Nature, 2015

879 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology

View Paper: https://www.semanticscholar.org/paper/7f6d430f262e113b761d7f48aca3ef420df043e9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Guido Kroemer
2. L. Galluzzi
3. Douglas R. Green
4. D. Klionsky
5. S. Gordon
6. R. Yadav
7. R. Kang
8. H. Chae

In Epidemiology

1. Guido Kroemer
2. L. Galluzzi
3. Douglas R. Green
4. D. Tang
5. R. Kang
6. Beth Levine
7. D. Klionsky
8. Jiao Liu

Citations in the corpus

• Autophagy-Dependent Ferroptosis: Machinery and Regulation (2020, background): “, 2018), reticulophagy regulator 1 (RETREG1/FAM134B) (Khaminets et al., 2015), reticulon 3 (RTN3) (Grumati et al.”
• Phagocytosis: An Immunobiologic Process. (2016, background): “, 2016) and ER-phagy and turnover (Khaminets et al., 2015).”
• Autophagy during viral infection — a double-edged sword (2018, background): “Recently, flaviviruses were shown to use the viral protease NS3 to directly cleave the ER-localized autophagic receptor reticulophagy regulator 1 (FAM134B; also known as RETREG1), thereby inhibiting FAM134B-mediated ER degradation (reticulophagy) 96, 97 (FIg.”
• Molecular definitions of autophagy and related processes (2017, neutral): “…that reticu-lophagy constitutes a specific form of macroautophagy that relies on the autophagy receptors Atg39 and Atg40 (in yeast), or their mammalian orthologue family with sequence similarity 134 member B (FAM134B) (in human and mouse cells) (Khaminets et al , 2015; Mochida et al , 2015).”
• Mechanisms of Selective Autophagy (2016, neutral): “In mammalian cells FAM134B, the functional counterpart of Atg40 mediates ER-phagy during nutrient starvation [104].”
• ER stress: Autophagy induction, inhibition and selection (2015, background): “(G) In mammals, the autophagy receptor FAM134B interacts with LC3 and GABARAP, and facilitates ER turnover by reticulophagy.(175) Similarly, yeast specific reticulophagy is Atg39 and Atg40 dependent.”
• A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress (2020, background): “These include Fam134B, RTN3L, ATL3, Sec62, CCPG1, and TEX264 in mammals and ATG39 and ATG40 in yeast (An et al., 2019; Chen et al., 2019; Chino et al., 2019; Fumagalli et al., 2016; Grumati et al., 2017; Khaminets et al., 2015; Mochida et al.; Smith et al., 2018).”
• Large-scale inference of gene function through phylogenetic annotation of Gene Ontology terms: case study of the apoptosis and autophagy cellular processes (2016, background): “Depending on the cellular component targeted for recycling, the macroautophagy process is known as mitophagy for mitochondria degradation (20, 21), nucleophagy for nuclei degradation (22), pexophagy for peroxisomes breakdown (12, 23), ribophagy for ribosomes (24), reticulophagy for endoplasmic retic”
• Autophagy-Independent Functions of the Autophagy Machinery (2019, background): “, 2016), damagecontrol (Fernández et al., 2018; Khaminets et al., 2015; Mathew et al., 2007), and cell death (Green et al.”