Molecular definitions of autophagy and related processes

By L. Galluzzi, Eric H. Baehrecke, Andrea Ballabio, P. Boya, J. M. Bravo-San Pedro, F. Cecconi, A. Choi, C. Chu, P. Codogno, Marina Colombo and 44 more. EMBO Journal, 2017

1,459 citations recorded by the source corpus.

Subfields: Epidemiology, Pharmacology, Plant Science

View Paper: https://www.semanticscholar.org/paper/16fdb44ac5cc1086955ef6c504ba0fbf7a7e0142

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Citations in the corpus

Exploring autophagy with Gene Ontology (2016, background): “The Cvt pathway [30] (GO:0032258, ‘protein localization by the Cvt pathway’; synonym: cytoplasm-to-vacuole targeting pathway) was not made a subtype of autophagy in GO because we restricted the use of the term ‘autophagy’ to represent only catabolic processes [31].”
Autophagy pathway: Cellular and molecular mechanisms (2018, background): “For additional information on ATG proteins not mentioned here as well as accessory regulatory proteins see a recent review.(2)”
Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States (2018, background): “The current understanding of the molecular mechanisms of autophagy and proteasomal degradation of proteins is reviewed in detail elsewhere (Galluzzi et al., 2017; VerPlank and Goldberg, 2017).”
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018, background): “Once engulfed, entotic cells are often eliminated by a RCD subroutine that occurs independently of BCL2 proteins and caspases [694, 704], but relies (at least in part) on a specific autophagy-related process commonly known as LC3-associated phagocytosis (LAP) [509, 705, 706].”
Mitochondrial metabolism and cancer (2017, background): “Besides fueling the oxidative mode of the TCA, citrate can also be converted into acetyl-CoA for export to the cytoplasm and nucleus [4, 81], where it can either be employed for fatty acid and cholesterol synthesis (to support the membrane need associated with intense proliferation) or used for acet”
Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion (2018, background): “Therefore, the initial autophagy induction triggered by CQ that we and others observed [29,49], could also be due to cellular stress that is caused by exposure to CQ rather than stimulating a specific non-canonical autophagic pathway [89].”
Autophagy-Independent Functions of the Autophagy Machinery (2019, background): “Autophagy relies on the formation, maturation, and subcellular relocalization of autophagosomes, ultimately resulting in their fusion with lysosomes (Galluzzi et al., 2017a) .”