Pluripotency of spermatogonial stem cells from adult mouse testis

By K. Guan, K. Nayernia, L. Maier, S. Wagner, R. Dressel, Jae Ho Lee, J. Nolte, Frieder Wolf, Manyu Li, W. Engel and 1 more. Nature, 2006

903 citations recorded by the source corpus.

Subfields: Molecular Biology, Reproductive Medicine

View Paper: https://www.semanticscholar.org/paper/7ee2588702cccf403a637b894dc28d405f06a425

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. K. Hochedlinger
2. M. Stadtfeld
3. S. Yamanaka
4. Kathrin Plath
5. José C. R. Silva
6. Jesús Gil
7. L. Vallier
8. M. Matzuk

In Reproductive Medicine

1. Ankur K. Nagaraja
2. M. Matzuk
3. M. Edson

Citations in the corpus

• Induced pluripotency: history, mechanisms, and applications. (2010, background): “2004) and adult (Guan et al. 2006; Seandel et al. 2007; Ko et al. 2009) mouse testicular cells.”
• Spermatogenesis in fish. (2010, background): “In adult mammals, recent findings suggest the presence of an SSC subpopulation that is totipotent and able to form different cell types (Guan et al., 2006; Conrad et al. 2008).”
• Epigenetic reprogramming and induced pluripotency (2009, background): “…cells from PGCs (Durcova-Hills et al., 2006) and that of multipotent germline stem (mGS) cells from germ line stem (GS) cells (Conrad et al., 2008; Guan et al., 2006; KanatsuShinohara et al., 2004; Seandel et al., 2007) is thought to be even less efficient, ranging from 1-3% and around 0.001%,…”
• The mammalian ovary from genesis to revelation. (2009, background): “Interestingly, it is now possible to produce pluripotent stem cells from mouse testis (748, 749) and adult human testis (750).”
• Strategies and new developments in the generation of patient-specific pluripotent stem cells. (2007, background): “Germline competent pluripotent stem cells were also generated from adult mouse testes, which were designated multipotent adult germline stem (maGS) cells (Guan et al., 2006).”
• Senescence impairs successful reprogramming to pluripotent stem cells. (2009, background): “…al., 2007; Tesar et al., 2007); embryonic germ (EG) cells from primordial germ cells (Matsui et al., 1992; Resnick et al., 1992); and multipotent germ stem (mGS) cells from explanted neonatal or adult mouse testicular cells (Guan et al., 2006; KanatsuShinohara et al., 2004b; Seandel et al., 2007).”
• The biology of infertility: research advances and clinical challenges (2008, background): “Adult mouse spermatogonial stem cells show plasticity and can transition into multipotent cells with the potential to differentiate into all three germ cell layer”