Association between telomere length in blood and mortality in people aged 60 years or older.

By R. Cawthon, Ken R. Smith, E. O'Brien, A. Sivatchenko, R. Kerber. The Lancet, 2003

1,759 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/7eb23ab51164a324ebd9200fee73afe9a6e50429

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In Physiology

Citations in the corpus

Trends in oxidative aging theories. (2007, background): “Even more interesting is the finding that telomere length is a statistical predictor of survival in humans over 60 [313] and mortality and morbidity in several age-related diseases [314].”
Telomeres: Linking stress and survival, ecology and evolution (2010, background): “…studied over a 20 year period, individuals > 60 years of age with shorter than average blood cell telomeres had lower survival, due to higher mortality from heart and infectious disease, than did individuals of the same age with longer than average blood cell telomeres (Cawthon et al., 2003).”
The epigenetic regulation of mammalian telomeres (2007, background): “Finally, a number of environmental factors (such as smoking, obesity and stress) have been shown to accelerate the rate of telomere shortening, and might therefore also have an impact on chromatin modifications at telomeres and the expression of subtelomeric gene”
Telomeres and aging. (2008, background): “One such study has correlated shorter leukocyte telomere lengths at age 60 with a three times higher risk of heart disease and an eightfold increase in risk of infection-related death (36), thereby associating measured relative cellular aging with disease and life expectancy.”
Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. (2006, neutral): “insulin resistance (8), obesity (9), atherosclerosis (10–12), vascular dementia (13), and mortality due to heart disease (14).”
Telomeres and human disease: ageing, cancer and beyond (2005, background): “In addition, a correlation between telomere length and risk of death from heart disease or infections has been recently observe”
Telomere length, stem cells and aging. (2007, background): “Indeed, a correlation between telomere length and risk of death from heart disease or infections has been reporte”
Increased brood size leads to persistent eroded telomeres (2014, background): “ORIGINAL RESEARCH ARTICLE published: 22 April 2014 doi: 10.3389/fevo.2014.00009 Increased brood size leads to persistent eroded telomeres”
Telomeres and telomerase. (2002, neutral): “infections are higher in elderly individuals with shorter average telomere length in their blood cells than in people with longer telomeres (Cawthon et al. 2003).”