Molecular analysis of mammalian circadian rhythms.

By Steven M. Reppert, D. Weaver. Annual Review of Physiology, 2001

1,488 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Plant Science

View Paper: https://www.semanticscholar.org/paper/7dfdad9b1ec52253a778b9ef5e3f960eb70d9c84

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Citations in the corpus

Extensive and divergent circadian gene expression in liver and heart (2002, background): “; endogenous oscillators that generate transcriptional rhythms thought to be important for the daily timing of physiological processe”
Major depressive disorder. (2008, neutral): “Circadian rhythm is a roughly 24-hour cycle of biochemical, physiological, and behavioral processes under control of internal clock [100-102].”
microRNA modulation of circadian-clock period and entrainment. (2007, neutral): “An internal timekeeping mechanism—the ‘‘circadian’’ clock—has arisen in nearly all organisms that allows them to adapt their physiological and behavioral process to a cyclic 24 hr world (Reppert and Weaver, 2001).”
Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. (2006, methodology): “Circadianentrained adult mice were transferred to constant darkness for 48 hr and then were either kept in darkness (DD), or exposed during subjective night to a light pulse of 2, 4, or 6 hr (LP2, LP4, LP6), a stimulus previously shown to be sufficient to trigger a behavioral shift in circadian rhyt”
The circadian clock: pacemaker and tumour suppressor (2003, background): “The levels of mRNAs and proteins of these circadian genes, except those of Clock and CK1e , oscillate throughout the 24-hour perio”
Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters (2003, background): “It is known that light exposure at night differentially affects the circadian clock machinery depending upon whether it is applied in the first or the second part of the night (Reppert and Weaver, 2001).”
Physiology of circadian entrainment. (2010, background): “The control of per, and presumably cry, expression, both for its endogenous cycling and its light-induced activity, is driven by CRE elements in its promoter region, as well as by E-box elements that respond to BMAL-CLOCK transcriptional activation (252, 413).”
Light at night increases body mass by shifting the time of food intake (2010, background): “Mice lacking the vasoactive intestinal peptide receptor 2 pathway, which plays an important role in SCN communication (11), have metabolic abnormalities similar to those in Clock-mutant mice (12).”
Circadian genes, rhythms and the biology of mood disorders. (2007, background): “…The primary molecular clock is located in the suprachiasmatic nucleus (SCN) in the hypothalamus, and consists of a transcriptional feedback loop which cycles over the course of approximately twenty-four hours in the absence of environmental input (Reppert and Weaver, 2001;Ko and Takahashi, 2006).”
Genetics and animal domestication: new windows on an elusive process (2006, background): “Genes expressed within the SCN affect the amount of timing of hormones released from the pineal gland, and the hypothalamus (Reppert & Weaver, 2001).”
Dopamine and retinal function (2004, background): “These additional pigments appear to account for the finding that nominally blind rodents still retain rhythms of locomotor activity [66] and still show light-dependent entrainment of the suprachiasmatic nucleus (SCN) [67], where the main clock of the body is located [68].”
Retinoid-related orphan receptors (RORs): critical roles in development, immunity, circadian rhythm, and cellular metabolism (2009, background): “The oscillators in peripheral tissues operate in a self-sustained, cell-autonomous manner [Isojima et al., 2003; Ko and Takahashi, 2006; Liu et al., 2007a; Reppert and Weaver, 2001; Reppert and Weaver, 2002; Ripperger and Schibler, 2001; Schibler and Sassone-Corsi, 2002].”
Coordination of circadian timing in mammals (2002, background): “The focal point of this system is a master clock, located in the suprachiasmatic nuclei (SCN) of the anterior hypothalamus, which orchestrates the circadian programm”