Central role of Drosophila SU(VAR)3–9 in histone H3‐K9 methylation and heterochromatic gene silencing
By Gunnar Schotta, Anja Ebert, V. Krauss, Andreas Fischer, Jan Hoffmann, S. Rea, T. Jenuwein, R. Dorn, G. Reuter. EMBO Journal, 2002
687 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/7dc3cdbf2e4822bddfb5dc79453b84a0747e9de7
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Citations in the corpus
- Histone and chromatin cross-talk. (2003, background): “Work using the polytene chromosomes of Drosophila has indeed indicated distinct banding patterns of histone modifications correlating with large transcriptionally competent or silenced regions [31,52,75,76].”
- Transcriptional Silencing of Transposons by Piwi and Maelstrom and Its Impact on Chromatin State and Gene Expression (2012, neutral): “HP1 proteins are known to interact with H3K9 methyltransferases (Schotta et al., 2002).”
- A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. (2004, background): “In Su(var)2-5 (HP1) mutants, H3-K9 methylation and pericentric accumula- 1256 GENES & DEVELOPMENT tion of SU(VAR)3-9 remains unaltered (Schotta et al. 2002).”
- Chromatin Structure and the Inheritance of Epigenetic Information (2010, background): “Some of the modifiers of variegation — for example, heterochromatin protein 1 (HP1, also known as suppressor of variegation 205 ( SU(VAR)205 )), SU(VAR)3-7 or SU(VAR)3-9 (Ref”
- Arabidopsis TFL2/LHP1 Specifically Associates with Genes Marked by Trimethylation of Histone H3 Lysine 27 (2007, neutral): “mechanisms of HP1 association likely exist [25–27].”
- RNAi-mediated pathways in the nucleus (2005, background): “This methylation of histone H3, which is typical of heterochromatic regions, is mediated primarily by SU(VAR)3-9, the mutant form of which functions as a suppressor of PEV (Ref”
- Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites. (2002, background): “Purification of the ESC/E(Z) Methyltransferase Chromatographic fractionation of Drosophila embryonic methylated histones at and around the centromeric region (Schotta et al., 2002).”
- Global Quantitative Modeling of Chromatin Factor Interactions (2014, background): “…complex components Pho – dSFMBT [21], Polycomb-repressed chromatin mark and binding protein Pc - H3K27me3 [22], heterochromatin mark and binding protein H3K9me3 - HP1 [23], gypsy insulator complex components CP190 - mod(mdg4) [24], and heterochromatin mark and writer H3K9me3 - Su(var)3-9 [25].”