Th17 cells in human disease
By L. Tesmer, Steven K. Lundy, Sujata Sarkar, D. Fox. Immunological Reviews, 2008
1,146 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/7afb3632c936173d7647ecafe1e9269858616537
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In Immunology
Citations in the corpus
- Immune System to Brain Signaling: Neuropsychopharmacological Implications (2011, background): “…disorders are pharmacologic strategies that target IL-17 or Th17 cells through the inhibition of cytokines or transcription factors which promote Th17 differentiation including IL-23 and retinoic acid receptor (RAR)-related orphan receptor C (RORc) (Boissier et al., 2008; Tesmer et al., 2008).”
- Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis (2010, positive): “Dovepress systemic administration of IL-12 in mice leads to anti-tumor activity(7,65) and IL-23 may promote tumor formation.(5) Lastly, while ustekinumab did not help in inhibiting RRMS, it is noteworthy that it did not create any neurological events as other biological agents, such as anti-TNF-α th”
- Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis. (2011, background): “DISCUSSION Th17 T cells have been implicated in several autoimmune diseases in model systems, as well as in human diseases (Tesmer et al., 2008; Abraham and Cho, 2009; Di Cesare et al., 2009; Gaffen, 2009; Crome et al., 2010).”
- MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis (2009, background): “Discussion T H -17 cells are critically involved in the pathogenesis of chronic autoimmune diseases, including multiple sclerosi”
- Evidence for a cross-talk between human neutrophils and Th17 cells. (2010, background): “Subsequently, we verified whether human neutrophils and Th17 cells co-localize in inflamed tissues isolated from selected inflammatory diseases in which Th17 cells have been shown to infiltrate and play a pathogenic role, namely CD and RA.(2;11) In CD, confocal microscopy analysis performed on gut s”
- Psychoneuroimmunology Meets Neuropsychopharmacology: Translational Implications of the Impact of Inflammation on Behavior (2012, background): “Th17 cells have been recently recognized as a distinct, highly pro-inflammatory T-cell subset that may have a fundamental pathophysiologic role in inflammatory disorders (Acosta-Rodriguez et al, 2007; Annunziato et al, 2007; Wilson et al, 2007; Tesmer et al, 2008; Damsker et al, 2010).”