Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans.
By Luigi Fontana, T. Meyer, S. Klein, J. Holloszy. Proceedings of the National Academy of Sciences of the United States of America, 2004
925 citations recorded by the source corpus.
Subfields: Nutrition and Dietetics, Pediatrics, Perinatology and Child Health, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/79c7b6390a910b59448fb8a6618e06ad29fd8ece
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Citations in the corpus
- Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial. (2006, neutral): “Age, mean (SD) [range], y 37 (7) [27-47] 39 (5) [30-45] 36 (6) [28-45] 38 (8) [26-49]”
- An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. (2007, background): “In humans, DR decreases the incidence of age-dependent diseases, including atherosclerosis and cancer [2, 3].”
- An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. (2007, background): “Some studies suggest that health benefits can be manifested from short-term reductions in caloric intake (68, 99, 274, 275), but there are currently no results from well-controlled studies involving long-term CR.”
- Ageing and neuronal vulnerability (2006, background): “Studies of the effects of dietary restriction a manipulation that can retard ageing processes in rodents, monkeys and humans, indicate that this might be the cas”
- Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma. (2007, background): “Caloric restriction (CR) improves numerous health indicators in rodents, monkeys, and humans, including those associated with risk of cardiovascular disease, type 2 diabetes, and cancers [19] [20] [21].”
- How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). (2010, background): “Hence and due to additional findings (Fontana et al., 2004; Heilbronn et al., 2006; Ingram et al., 2006a; Weindruch, 2006; Fontana and Klein, 2007) it appears possible that CR extends life span in primates and/or humans.”
- The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases (2018, background): “Compliance with a calorie-restricted diet over the long term is associated with mobilization of liver fat and improvement in cardiovascular risk.((137)) The specific macronutrient composition of the diet, over months to years, appears to be less relevant than the end result of sustained weight loss.”