A novel ubiquitin ligase is deficient in Fanconi anemia

By A. R. Meetei, J. Winter, A. Medhurst, M. Wallisch, Q. Waisfisz, H. V. D. Vrugt, A. Oostra, Zhijiang Yan, Chen Ling, C. Bishop and 3 more. Nature Genetics, 2003

626 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/78e2d9f6870b624f62b729c31887d39f32fff1d3

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Citations in the corpus

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. (2005, background): “…(NBS), Ataxia Telangiectasia (ATM), and Seckel Syn-The Netherlands drome (ATR) functionally intersect with the FA signaling2 Department of Radiation Oncology pathway (Andreassen et al., 2004; Meetei et al., 2003b;Dana-Farber Cancer Institute Nakanishi et al., 2002; Taniguchi et al., 2002b).”
How the fanconi anemia pathway guards the genome. (2009, methodology): “FANCL is an E3 ubiquitin ligase with a PHD domain that modifies FANCD2 and FANCI with a single ubiquitin moiety, employing UBE2T as an E2 (57, 88, 91).”
Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins (2007, background): “One of the main functions of this complex is to monoubiquitylate FANCD2 and FANC”
Spectrum of sequence variations in the FANCA gene: An International Fanconi Anemia Registry (IFAR) study (2003, background): “, 2004], and eight associated genes have been identified [Strathdee et al., 1992; Fanconi Anemia/Breast Cancer Consortium, 1996; Lo Ten Foe et al., 1996; de Winter et al., 1998, 2000a, b; Timmers et al., 2001; Howlett et al., 2002; Meetei et al., 2003].”