How the fanconi anemia pathway guards the genome.

By George‐Lucian Moldovan, A. D’Andrea. Annual Review of Genetics, 2009

634 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/0b47e88634535ffb919d4c5f2dc07bd7239ee04a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

Citations in the corpus

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. (2011, background): “For instance, when DNA breaks occur during DNA replication, the FA core complex monoubiquitylates the FA proteins FANCD2 and FANCI in a manner that promotes their localization to HR foci (Alpi and Patel 2009; Moldovan and D’Andrea 2009).”
A Distinct Replication Fork Protection Pathway Connects Fanconi Anemia Tumor Suppressors to RAD51-BRCA1/2 (2012, background): “BLM helicase interacts with both FA and BRCA networks (Chu and Hickson, 2009; Deans and West, 2009; Moldovan and D’Andrea, 2009).”
Homologous recombination and human health: the roles of BRCA1, BRCA2 and associated proteins (2015, background): “Some of the congenital abnormalities are similar to those described in FA-D1 and FA-N children with biallelic BRCA2 and PALB2 mutation, respectively; however, the absence of a malignancy in the olderchild is distinct (Moldovan and D’Andrea 2009).”
Regulation of homologous recombination in eukaryotes (2010, background): “FANCJ, a component of the Fanconi Anemia pathway (see sidebar) (105), exhibits a 5′ → 3′ directionality, in contrast to the RecQ family helicases.”
The DNA Damage Response: Making it safe to play with knives (2010, background): “The FANCI-FANCD2 (ID) complex lies at the heart of the FA pathway and becomes monoubiquitinated on both subunits by the FANCL ubiquitin ligase within the FA core complex (Moldovan and D’Andrea, 2009).”