Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body

By Chia-Lin Wu, S. Xia, Tsai-Feng Fu, Huaien Wang, Ying-hsiu Chen, Daniel Leong, Ann-Shyn Chiang, Tim Tully. 2007

183 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Ecology, Evolution, Behavior and Systematics, Immunology

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Citations in the corpus

Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila (2014, positive): “In this regard, we note that previous studies demonstrated a role for NMDA receptors in olfactory memory (Wu et al., 2007; Miyashita et al., 2012).”
Short and Long-term memory in Drosophila require cAMP signaling in distinct neuron types (2009, background): “Given the known role for NMDA receptors in the ellipsoid body [ 27 ], our results suggest the interesting hypothesis that there is a dynamic circuit-level interaction rather than just a biochemical consolidation within MBs.”
Competing dopamine neurons drive oviposition choice for ethanol in Drosophila (2013, background): “(B) Disrupting transmission in the PPM3 neurons (33) decreased preference [n = 12–18 per strain; ANOVA: F(2,49) = 20.”
The Mushroom Body of Adult Drosophila Characterized by GAL4 Drivers (2009, unknown): “…Le, & Davis, 2001); 2: (Peng, Xi, Zhang, Zhang, & Guo, 2007); 3: (Ramaekers et al., 2005); 4: (Masuda-Nakagawa, Tanaka, & O’Kane, 2005); 5: (Wu et al., 2007); 6: (Fushima & Tsujimura, 2007); 7: (Connolly et al., 1996); 8: (Kurusu et al., 2002); 9: (Tanaka, Tanimoto, & Ito, 2008); 10:…”
Glutamate is an inhibitory neurotransmitter in the Drosophila olfactory system (2013, methodology): “Fly stocks were published as follows: OK371-Gal4 (II) (1), UAS-CD8:GFP (II and III) (2), pebbledGal4 (X) (3), UAS-nsyb:GFP (4), GH146-Gal4 (II) (5), UAS-P2X2 (III) (6), NP3056-Gal4 (III) (7), UAS-GluClα RNAi (II) (8, 9), UAS-dicer2 (X) (8).”
Rapid Consolidation to a radish and Protein Synthesis-Dependent Long-Term Memory after Single-Session Appetitive Olfactory Conditioning in Drosophila (2008, methodology): “Wu et al. (2007) proposed that aversive LTM consolidation involved “transfer” from MB to the ring neurons in the EB.”
Mg2+ Block of Drosophila (2012, unknown): “While previous studies have shown that hypomorphic mutations in Drosophila NMDARs (dNMDARs) disrupt both associative learning (LRN) and LTM formation without affecting ARM (Wu et al., 2007; Xia et al., 2005), it is still not clear how Mg 2+ block is involved in these processes.”
Drosophila ORB protein in two mushroom body output neurons is necessary for long-term memory formation (2013, background): “The consolidation of odor–shock memories presumably involves multiple nodes in the underlying neuronal network, including antenna lobes (10), mushroom body (MB) (11–13), ellipsoid body (14), and two dorsal anterior lateral (DAL) neurons (15).”