Protein turnover via autophagy: implications for metabolism.

By N. Mizushima, D. Klionsky. Annual review of nutrition, 2007

807 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Parasitology

View Paper: https://www.semanticscholar.org/paper/7742319a5a21c02e3bff85ff5805777330a2e9ef

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Kay F Macleod
2. J. Forbes
3. R. Yadav
4. H. Chae
5. M. Cooper
6. M. Matz
7. B. Willis
8. Danielle Glick

In Epidemiology

1. Kay F Macleod
2. Danielle Glick
3. Sandra Barth
4. H. Chae
5. Hyung-Ryong Kim
6. R. Yadav
7. H. Rashid
8. A. Iwasaki

In Parasitology

1. R. Yadav
2. H. Chae
3. Hyung-Ryong Kim
4. H. Rashid
5. N. Mizushima
6. D. Klionsky

Citations in the corpus

• ER stress: Autophagy induction, inhibition and selection (2015, background): “Furthermore, autophagy is crucial for cell growth and differentiation, tumor suppression, innate and adaptive immunity, life-span extension, and cell death.(62) In this way, autophagy plays a substantial role throughout the entire life span of an organism.”
• Genetic variation in responses to a settlement cue and elevated temperature in the reef-building coral Acropora millepora (2009, background): “…unexpected observation leads to the following speculation: protein balance is determined by the relative rates of synthesis and degradation and, in the absence of exogenous nutrients, cells use free amino acids derived from degraded proteins for new protein synthesis (Mizushima & Klionsky 2007).”
• Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry. (2009, background): “Autophagy is another possible source of amino acids, as it is well-documented that autophagy liberates and thereby increases the free amino acid pools (36, 37).”
• Autophagy: cellular and molecular mechanisms (2010, background): “In mammalian cells, phagophore membranes appear to initiate primarily from the ER [11,12] in dynamic equilibrium with other cytosolic membrane structures, such as the trans-Golgi and late endosomes [5,9,13] and possibly even derive membrane from the nuclear envelope under restricted conditions [14].”
• Autophagy: process and function. (2007, background): “Autophagy is a general term for the degradation of cytoplasmic components within lysosomes (Cuervo 2004; Levine and Klionsky 2004; Shintani and Klionsky 2004; Klionsky 2005, 2007; Mizushima and Klionsky 2007).”
• Autophagy in the pathogenesis of disease. (2008, neutral): “The molecular cascade that regulates and executes autophagy has been the subject of recent, comprehensive reviews (Klionsky, 2007; Maiuri et al., 2007a; Mizushima and Klionsky, 2007; Rubinsztein et al., 2007).”
• Mechanisms of diabetic complications. (2013, background): “This process is facilitated by a number of autophagy-related proteins (398).”
• Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling (2009, background): “It has also been studied extensively as a critical survival mechanism during starvation conditions (1, 2).”