Integrated genomic characterization of adrenocortical carcinoma

By G. Assié, E. Letouzé, M. Fassnacht, A. Jouinot, Windy Luscap, O. Barreau, H. Omeiri, S. Rodriguez, K. Perlemoine, F. René-Corail and 24 more. Nature Genetics, 2014

627 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Surgery

View Paper: https://www.semanticscholar.org/paper/7737717fef19a7543b252fb2820f3f5adfaf92bd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Olivier Elemento
2. Arul M. Chinnaiyan
3. Hans Clevers
4. C. Sawyers

In Genetics

1. Hans Clevers
2. R. Nusse
3. C. Sawyers
4. Olivier Elemento
5. Arul M. Chinnaiyan
6. Pengfei Lu

In Surgery

1. R. Nusse
2. Hans Clevers

Citations in the corpus

• Wnt/ b -Catenin Signaling, Disease, and Emerging Therapeutic Modalities (2017, background): “…recently, inactivating mutations were first reported in the E3 ligase genes Rnf43 in pancreas cancer (Wu et al., 2011) and Znrf3 in adrenocortical carcinoma (Assié et al., 2014) and subsequently seen in multiple other cancers, adding these two genes to the list of Wnt pathway tumor suppressors.”
• Integrative clinical genomics of advanced prostate cancer (2015, positive): “Through integrative analysis, we identified alterations in RNF43 and ZNRF3, which were recently described in colorectal, endometrial, and adrenocortical cancers (Assié et al., 2014; Giannakis et al., 2014) and were mutually exclusive with APC alterations (Figure 6A).”