Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate.

By Randy L. Buckner. Neuron, 2004

1,573 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/7639e26125a221e7ba50471db43f515b5375c12e

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Citations in the corpus

Age Differences in Deactivation: A Link to Cognitive Control? (2007, background): “Almost all functional neuroimaging studies of aging and cognitive control have focused on age differences in the positive activation of active-task regions (see recent reviews by Rajah & D’Esposito, 2005; Reuter-Lorenz & Lustig, 2005; Buckner, 2004; Hedden & Gabrieli, 2004).”
Altered resting state networks in mild cognitive impairment and mild Alzheimer's disease: An fMRI study (2005, methodology): “Evidence for this comes from studies of memory retrieval: although most tasks show a decrease in activity in the default mode network, tasks comparing successful memory retrieval to correctly rejecting new items show an increase in activity in (posterior parts of) the network [Buckner, 2004].”
Growing together and growing apart: Regional and sex differences in the lifespan developmental trajectories of functional homotopy (2010, background): “Based on evidence of decreasing lateralization in normal aging (Cabeza et al., 2002; Buckner, 2004; Li et al., 2009; Park and Reuter-Lorenz, 2009), we also predicted quadratic or cubic age-related changes in homotopic RSFC.”
Molecular, Structural, and Functional Characterization of Alzheimer's Disease: Evidence for a Relationship between Default Activity, Amyloid, and Memory (2005, background): “One hypothesis is that the retrieval success effect reflects cortical regions interacting with the medial temporal lobe during memory retrieval (Buckner and Wheeler, 2001; Shannon and Buckner, 2004).”
Frontal-hippocampal double dissociation between normal aging and Alzheimer's disease. (2005, methodology): “On the other hand, differences between AD and nondemented aging have been recognized (Morrison and Hoff, 1997; Albert, 1998; Morris, 1999; Price et al., 2001; Uylings and de Brabander, 2002).”
What is normal in normal aging? Effects of Aging, Amyloid and Alzheimer’s Disease on the Cerebral Cortex and the Hippocampus (2014, background): “For instance, while degeneration of the medial temporo-parietal memory network is characteristic for AD, change in a frontostriatal network supporting executive functions has been proposed as a hallmark of healthy aging (Buckner, 2004; Head et al., 2005) (see Fig.”
Disruption of large-scale brain systems in advanced aging. (2007, methodology): “Implications of Functional Disruption of Large-Scale Brain Systems in Normal Aging Accumulating evidence suggests that aging is associated with multiple cascades that arise from separate pathophysiological processes, each associated with distinct cognitive sequelae (Hedden and Gabrieli, 2004; Buckne”
Age-related Changes in Brain Activity across the Adult Lifespan (2006, background): “…theory in this group is the frontal lobe theory of aging, which suggests that many age-related changes in cognition are due to the particular vulnerability of the frontal lobes to the structural and neurochemical changes that occur with age (Buckner, 2004; Raz, 2000; Raz et al., 1997; West, 1996).”
The Adaptive Brain: Aging and Neurocognitive Scaffolding (2009, background): “Both the Buckner (2004) proposition and the frontal compensation for hippocampal deﬁcits argu-ment could be correct, if one considers the possibility the realm of healthy elderly, one sees a compensatory relationship between the two structures, but shrinkage and dysfunction may reach a critical…”
Revisiting the dedifferentiation hypothesis with longitudinal multi-cohort data. (2007, background): “…1994), whereas between-person differences in change related to deficiencies such as prefrontal functioning and dopaminergic neuromodulation (see Buckner, 2004) may predominantly point to heterogeneity in timing (i.e., these changes are assumed to eventually afflict most members of the aging…”
Hierarchical Fully Convolutional Network for Joint Atrophy Localization and Alzheimer’s Disease Diagnosis using Structural MRI (2018, background): “Brain atrophy associated with dementia is an important bio-marker of AD and its progression, especially considering that the atrophic process occurs even earlier than the appearance of amnestic symptoms [2].”
Changes in structural and functional connectivity among resting-state networks across the human lifespan (2014, background): “Finally, the current findings are suggestive of changes to structural integrity (including myelin deterioration and vascular insult; Buckner, 2004; Tomasi and Volkow, 2012) leading to increased reliance on polysynaptic structural paths and thus increased functional coordination over them (see also…”
Effects of memory training on cortical thickness in the elderly (2010, background): “A persistent challenge in cognitive aging research is to illuminate and track the various factors contributing to the fact that someage gracefullywhereas other decline more rapidly (Buckner, 2004).”
Frontal circuitry degradation marks healthy adult aging: Evidence from diffusion tensor imaging (2005, background): “Although a large body of studies (for reviews, Buckner, 2004; Hedden and Gabrieli, 2004; Raz, 1999; but see Greenwood, 2000) supports the position that as a group older, healthy individuals are likely to exhibit poorer executive functioning than younger individuals, we do not have neuropsychologic”