Nutritional Control of Reproductive Status in Honeybees via DNA Methylation

By R. Kucharski, J. Maleszka, S. Forêt, R. Maleszka. Science, 2008

1,083 citations recorded by the source corpus.

Subfields: Ecology, Evolution, Behavior and Systematics, Genetics, Insect Science

View Paper: https://www.semanticscholar.org/paper/75c7f65f00fc289375d600b18edafcaf2a5e7bc5

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In Ecology, Evolution, Behavior and Systematics

In Genetics

In Insect Science

Citations in the corpus

The Physiological and Genomic Bases of Bumble Bee Social Behaviour (2015, background): “Other studies have indicated that decreasing methylation levels biases developing honey bee larvae to queen rather than worker development (Kucharski et al., 2008), suggesting that methylation plays a general role in regulating reproductive potential in bees.”
Epigenetics and aging (2016, background): “Similarly, different environmental stimuli, including diet, cause differential alterations of stored epigenetic information to create a striking contrast inphysical appearance, reproductive behavior, and life spanof queen and worker honeybees, despite their identical DNA content (16).”
Epigenetics and the environment: emerging patterns and implications (2012, background): “Through yet-unknown mechanisms this brings about differential DNA methylation and the differential expression of many genes between queen and worker larvae, through the action of the de novo methyltransferase DNMT3 (Ref”
Standard methods for artificial rearing of Apis mellifera larvae (2013, methodology): “…time, tongue length, spermatheca, chaetotaxy of metathoric legs, sting lancet, mandibular notch, weight at adult emergence and juvenile hormone titer are used for differentiation (Weaver, 1974; Asencot and Lensky, 1976, 1984; Shuel and Dixon, 1986; Kucharski et al., 2008; Kamakura, 2011).”
Epigenetics for behavioral ecologists (2013, background): “These divergent behaviors correlate with different patterns of methylation among bee brains, and can be reproduced by experimentally manipulating methyltransferase (the enzyme responsible for methyl group maintenance) with RNA interference technology (RNAi; Kucharski et al. 2008).”
Endocrine Control of Insect Polyphenism (2012, background): “A second important point is the annotation of a complete complement of DNA methyltransferases (Walsh et al., 2010), bringing into focus the possible role of epigenetic alteration in the development of alternative phenotypes similar to findings in the honey bee (Kucharski et al., 2008).”
Standard methods for molecular research in Apis mellifera (2013, background): “Several studies report on the application of dsRNA to eggs and larvae whether by injection (Aronstein and Salivar, 2005; Beye et al., 2002; Maleszka et al., 2007) or ingestion (Aronstein et al., 2006; Patel et al., 2007; Kucharski et al., 2008; Nunes and Simoes, 2009; Liu et al., 2010).”
Does the field of animal personality provide any new insights for behavioral ecology (2017, background): “Similarly, whether or not a female honeybee is raised as a queen or a worker is determined by epigenetic modification triggered by differential feeding (Kucharski et al. 2008).”
DNA Demethylation Dynamics (2011, background): “The significant impact of DNA methylation patterns on cell and organismal fate is perhaps most graphically exemplified in honeybees, in which differential DNA methylation determines whether the bee will be a worker or a queen (Kucharski et al., 2008).”
The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers (2010, background): “In honey bees, feeding of newly hatched larvae destined to become queens with royal jelly leads to metabolic acceleration and increased growth driven by global but relatively subtle changes in the expressional levels of a large number of ubiquitous genes [2,3,10].”
Nuclear reprogramming to a pluripotent state by three approaches (2010, background): “The composition of royal jelly is unknown, but its effects can largely be mimicked by decreasing the levels of a single repressive epigenetic regulator, the DNA methyltransferase DNMT3 (ref”