Mechanism of Divergent Growth Factor Effects in Mesenchymal Stem Cell Differentiation

By I. Kratchmarova, M. Haack-Sørensen, M. Kassem, Matthias Mann. Science, 2005

596 citations recorded by the source corpus.

Subfields: Molecular Biology, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/754d0b51413a269fc3a2e17067e1b5eff2017949

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Citations in the corpus

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (2006, background): “…ª2006 Elsevier Inc. 635 downstream protein kinases and their substrates (Hunter, 2000; Pawson and Nash, 2003), and several MS studies have focused on tyrosine-phosphorylation ‘‘early events’’ after growth-factor treatment (Blagoev et al., 2003, 2004; Kratchmarova et al., 2005; Zhang et al., 2005).”
Comparative evaluation of mass spectrometry platforms used in large-scale proteomics investigations (2005, background): “For example, researchers often restrict their confident protein identifications to those identified by two or more peptide”
The Regulation of Differentiation in Mesenchymal Stem Cells (2010, unknown): “PDGF has been shown to inhibit osteogenic differentiation (Gruber et al. , 2004; Kratchmarova et al. , 2005).”
SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function. (2008, background): “, 2002), which has unique advantages for quantitative and functional proteomics because of its inherent accuracy of quantitation and the ease of interpretation of MS results (Blagoev et al., 2004; Kratchmarova et al., 2005).”
Cell-signalling dynamics in time and space (2006, background): “The first challenge is beginning to be addressed by nascent quantitative proteomics of post-translational modifications 53,54 .”
Decoding signalling networks by mass spectrometry-based proteomics (2010, unknown): “Chemically blocking the PI3K pathway converted the PDGF pathway into a differentiation signa”
A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC) (2006, methodology): “By using three isotopically distinct forms of arginine and lysine, triple encoding SILAC allows comparison of three cell populations in a single experimen”
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (2008, background): “Moreover, antibody-mediated purification of tyrosinephosphorylated proteins can be used to enrich for protein kinases bearing this posttranslational modification (Kratchmarova et al., 2005).”