Functional significance of the cortico-subthalamo-pallidal 'hyperdirect' pathway.

By A. Nambu, H. Tokuno, M. Takada. Neurosciences research, 2002

1,305 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/7448e67a9486924366b9b380bcad6448b536fcda

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In Cellular and Molecular Neuroscience

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Citations in the corpus

Convergent evidence for abnormal striatal synaptic plasticity in dystonia (2009, neutral): “…in several models of movement disorder pathophysiology, including dystonia (Albin et al., 1989; DeLong, 1990; Gale et al., 2008; Mink, 1996, 2003; Nambu et al., 2000, 2002; Vitek, 2002), (3) the basal ganglia, andmost commonly their primary output structure the globus pallidus internum (GPi),…”
Functional neuroanatomy of the basal ganglia. (2012, positive): “…station of the indirect pathway), the STN also receives glutamatergic projections from the cerebral cortex (known as the hyperdirect pathway ) (see Nambu et al. 2002; Nambu 2004, 2005) and the ipsilateral thalamic caudal intralaminar nuclei (Sugimoto and Hattori 1983; Sugimoto et al. 1983; Royce…”
Triangulating a Cognitive Control Network Using Diffusion-Weighted Magnetic Resonance Imaging (MRI) and Functional MRI (2007, background): “As the primate tracing data show, there are multiple connections between the STN and ipsilateral sectors of the frontal cortex (Nambu et al., 2002).”
Confirmation of functional zones within the human subthalamic nucleus: Patterns of connectivity and sub-parcellation using diffusion weighted imaging (2012, background): “Direct cortical connections from and to the STN exist, forming the basis for the hyperdirect pathway in motor processing (Nambu et al., 1997, 2002).”
Whole-brain mapping of direct inputs to midbrain dopamine neurons. (2012, positive): “Anatomically, STh constitutes the ''hyperdirect pathway'' as well as the ''indirect'' pathway of the corticobasal ganglia loops (Nambu et al., 2002) (Figure 8C).”
A computational model of inhibitory control in frontal cortex and basal ganglia. (2011, neutral): “…by a salience detection mechanism implemented in the rIFG which directly projects to the STN to inhibit responding (Aron, Durston, et al., 2007; Eagle et al., 2008; Isoda & Hikosaka, 2008; Jahfari et al., 2012, 2011; Kühn et al., 2004; Mink, 1996; Nambu et al., 2000; Nambu, Tokuno, & Takada, 2002).”
The subthalamic nucleus in the context of movement disorders. (2004, background): “Primary motor cortex ®bres related to the leg, arm and face are represented from medial to lateral in the lateral portion of the STN, whereas the medial portion of the nucleus receives ®bres from the SMA, PMd and PMv in an inverse somatotopic distribution (leg, arm and face, respectively, represente”
Intrinsically motivated action-outcome learning and goal-based action recall: a system-level bio-constrained computational model. (2013, background): “The cortico-subthalamo-pallidal pathway is sometimes referred to as the hyperdirect pathway (Nambu et al., 2002).”
Functional MRI of Language in Aphasia: A Review of the Literature and the Methodological Challenges (2007, background): “, 1999) and with the concept that one function of the basal ganglia is to suppress undesired activity (e.g., Mink, 1996; Nambu et al., 2002).”
Insights into the neural basis of response inhibition from cognitive and clinical neuroscience. (2009, positive): “Finally, the response is terminated via a slower fronto-striatal indirect pathway (Nambu et al., 2002).”
Cortical and Subcortical Contributions to Stop Signal Response Inhibition: Role of the Subthalamic Nucleus (2006, methodology): “Basal-ganglia models suggest STN activation could occur either via the “hyperdirect” fronto-subthalamic pathway or via the “indirect” fronto-striatal–pallidal–subthalamic pathway (Alexander et al., 1990; Mink, 1996; Nambu et al., 2002).”