Placebo and Opioid Analgesia-- Imaging a Shared Neuronal Network

By Predrag Petrovic, E. Kalso, Karl Magnus Petersson, Martin Ingvar. Science, 2002

1,505 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Physiology

View Paper: https://www.semanticscholar.org/paper/73f909bae5802e9a82cc6111bed9ca2348f955cf

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Citations in the corpus

A common neurobiology for pain and pleasure (2008, background): “Recently, however, neuroscientists investigating opioid and placebo analgesi”
Brain Systems Mediating Cognitive Interference by Emotional Distraction (2006, background): “However, studies that have specifically associated the right vlPFC with the inhibition of negative emotions (Petrovic et al., 2002; Ochsner et al., 2004) suggest that greater activity in this region reflects enhanced inhibitory processes engaged to control the impact of distracting negative emotions”
The influence of negative emotions on pain: Behavioral effects and neural mechanisms (2009, positive): “The dorsal ACC has mainly been implicated in the cognitive modulation of pain affect (Faymonville et al., 2000; Wager et al., 2004) whereas the signal level in the perigenual ACC has been shown to increase during placebo analgesia (Bingel et al., 2006; Petrovic et al., 2002; Zubieta et al., 2005).”
Placebo and nocebo effects are defined by opposite opioid and dopaminergic responses. (2008, result): “Contrary to these findings, positive interrelationships between the activity of the PAG and subgenual anterior cingulate and amygdala have been noted in studies examining blood flow responses to placebo administration.(9,10) However, these measurements reflect the metabolic demands associated with s”
Activation of the opioidergic descending pain control system underlies placebo analgesia. (2009, methodology): “, 2000) and as previous studies observed heightened rACC-PAG functional connectivity under placebo analgesia (Bingel et al., 2006; Petrovic et al., 2002; Wager et al., 2007), we wanted to test whether these connections are opioid dependent.”
Dissociable effects of arousal and valence on prefrontal activity indexing emotional evaluation and subsequent memory: an event-related fMRI study (2004, background): “Specifically related to the involvement in emotional processing, right ventrolateral PFC has been implicated in the inhibition of negative emotions (Petrovic et al., 2002).”
Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation (2011, positive): “Similar to previous reports examining placebo analgesia (Petrovic et al., 2002; Wager et al., 2004), the present study finds increased OFC and ACC activation related to pain modulation.”
Social cognitive neuroscience: a review of core processes. (2007, background): “Indeed, individual differences in the ability to delay gratification as a child are highly predictive of achievement decades later (Metcalfe & Mischel 1999).”
Neurobiological Mechanisms of the Placebo Effect (2005, background): “Each of these regions, except those in the OFC and right VLPFC, have been shown to increase activation with delivery of an opiate analgesic (Firestone et al., 1996; Adler et al., 1997; Wagner et al., 2001; Petrovic et al., 2002).”
Conscious Expectation and Unconscious Conditioning in Analgesic, Motor, and Hormonal Placebo/Nocebo Responses (2003, background): “, 1999b) and neuroanatomical viewpoints (Petrovic et al., 2002).”
Descending pain modulation and chronification of pain (2014, neutral): “Descending noradrenergic projections to the spinal dorsal horns arise from the A5, the locus coeruleus (A6) and the Kölliker-Füse (A7) pontine noradrenergic nuclei, and these regions communicate with the RVM and PAG [84-87].”
The neural correlates of placebo effects: a disruption account (2004, methodology): “Petrovic et al. (2002) recently compared placeboinduced analgesia to opioid-induced analgesia and found that whereas both placebos and induced opioids led to similar changes in the rostral anterior cingulate and brainstem, only the placebo led to increased activity in right prefrontal cortex (x =…”
State-dependent opioid control of pain (2004, methodology): “Using positron emission tomography and an experimental pain model, Petrovic and colleague”