Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier.
By Y. Gilgun-Sherki, E. Melamed, D. Offen. Neuropharmacology, 2001
803 citations recorded by the source corpus.
Subfields: Biochemistry, Molecular Biology, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/739e813f146f7341e8ff9ac07051d187cee398ff
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Citations in the corpus
- Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications (2017, background): “Furthermore, the time, the method, and the dose of antioxidant administration as well as the stage of the disease are all key factors that should be taken into account when investigating the effects of antioxidant therapies in future studies [29, 30].”
- Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration (2015, neutral): “In the clinical setting, the prescription of antioxidants towards treatment of neurodegenerative diseases has been tested repeatedly on patients with neurodegenerative disorders (Galasko et al., 2012; Gilgun-Sherki et al., 2001; Gandhi and Abramov, 2012), without compelling results.”
- Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options (2009, methodology): “Recognition of upstream and downstream antioxidant therapy to oxidative stress has been proved an effective tool in alteration of any neuronal damage as well as free radical scavenging.”
- Role of ROS and Nutritional Antioxidants in Human Diseases (2018, background): “Antioxidants, either endogenously generated or externally supplied, are capable of scavenging ROS and reducing the oxidation of cellular molecules, thus alleviating OS (Gilgun-Sherki et al., 2001).”
- Studies on free radicals, antioxidants, and co-factors (2007, background): “It has been reported that the concentration of antioxidant varies within the different regions of the brain and some enzymatic antioxidants such as catalase are found in lower concentrations in the brain when compared to other tissues (Gilgun-Sherki et al 2001).”