Dishevelled controls cell polarity during Xenopus gastrulation

By John B. Wallingford, B. Rowning, K. Vogeli, U. Rothbächer, Scott E. Fraser, R. Harland. Nature, 2000

825 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/71fab1c43cfb2c474f6a482c923e8fb0712f32b3

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Citations in the corpus

• The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway (2003, background): “XWnt11, Xdsh, XJNK, tri/stbm) involved in non-canonical Wnt signalling in Xenopus or zebrafish (Heisenberg et al. 2000; Wallingford et al. 2000; Jessen et al. 2002; Pandur et al. 2002; Yamanaka et al. 2002).”
• Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. (2001, neutral): “Characteristic of Fz PCP sig- markers, we found that embryos injected dorsally with N-Daam1 RNA, while expressing normal levels of spenaling (Tada and Smith, 2000; Wallingford et al., 2000; Djiane et al., 2000), embryos injected dorsally with cific marker genes, exhibit defects in positioning and mo”
• Convergent extension: the molecular control of polarized cell movement during embryonic development. (2002, background): “In the converse experiment, an interfering mutant of Xwnt-11 severely disrupts conver- undergoing convergent extension, but is cytoplasmic in other cells (Wallingford et al., 2000).”
• Activation of Gβγ signaling downstream of Wnt-11/Xfz7 regulates Cdc42 activity during Xenopus gastrulation (2003, background): “, 2001) and causes a loss of cell polarization, which correlates with the inability of Xdd1-expressing cells to stabilize protrusions (Wallingford et al., 2000).”
• Casein Kinase Iε Modulates the Signaling Specificities of Dishevelled (2004, methodology): “The kinase assays were initiated by the addition of 2 g of GST-Jun(1-109) substrate protein, and 10 Ci of [ -32P]ATP in a volume of 25 l.”
• LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way (2004, background): “, 2001), which are regulated by a Wnt11/Fz pathway analogous to Dfz1/PCP signaling (Heisenberg et al., 2000; Tada and Smith, 2000; Wallingford et al., 2000).”
• Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. (2003, background): “These phenotypes are characteristic of defects in morphogenetic movements (Djiane et al. 2000; Tada and Smith 2000; Wallingford et al. 2000).”
• The Extracellular Matrix In Development and Morphogenesis: A Dynamic View (2009, background): “While non-canonical wnt planar cell polarity signaling is essential for bipolar protrusive activity (Wallingford and Harland, 2001; Wallingford et al., 2000), lack of integrin occupancy in these cells leads to increased frequency and randomization of cellular protrusions (Davidson et al., 2006).”