Sonic the Hedgehog

By F. Black. 2006

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Fibroblast heterogeneity in the cancer wound (2014, background): “Hedgehog (Hh) signaling mediates tumorigenesis in many types of cancer (Thayer et al., 2003; Bailey et al., 2009).”
Hedgehog Signaling in the Subventricular Zone Is Required for Both the Maintenance of Stem Cells and the Migration of Newborn Neurons (2007, background): “Hence, consistent with the previous results of other groups (Ahn and Joyner, 2005; Palma et al., 2005), we found that the majority of B cells in the ventral part of the SVZ appears to be responding to Hh signaling.”
Wnt signaling in the intestinal epithelium: from endoderm to cancer. (2005, background): “During chick and mouse development Sonic hedgehog (Shh) and Indian hedgehog (Ihh) play multiple roles in patterning of the gastrointestinal tract (Apelqvist et al. 1997; Litingtung et al. 1998; Ramalho-Santos et al. 2000; Sukegawa et al. 2000; Fukuda et al. 2003).”