Antibacterial activity of chitosans and chitosan oligomers with different molecular weights.

By H. No, N. Park, Shin-Ho Lee, S. Meyers. Journal of food microbiology, 2002

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Antibacterial effects of chitosan–tripolyphosphate nanoparticles: impact of particle size molecular weight (2014, background): “Its minimum inhibitory concentration (MIC) against Gram-negative bacteria varies from 100 to 10,000 lg/mL (Helander et al. 2001), whereas that against Gram-positive bacteria varies from 100 to 1,250 lg/mL (Bae et al. 2006; Jeon et al. 2001; Vishu Kumar et al. 2004; No et al. 2002).”
A future perspective in crop protection chitosan and its oligosaccharides (2014, background): “Chitosan and COS have attracted considerable interest due to their biological activities, namely, antimicrobial [4-11] and enhanced calcium and ferrum absorption [12-17] and so on.”
Modification of Chitosan for the Generation of Functional Derivatives (2019, background): “The medium pH is very important and CS loses its activity above pH 7, because of deprotonation and insolubility [83,120,127,130].”
Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications (2015, background): “5) and degree of acetylation of chitosan [183–185].”
Chitosan Nanocomposite Coatings for Food, Paints, and Water Treatment Applications (2019, background): “however, reported that the antimicrobial activity of chitosan was greater with lower molecular weight for Gram-negative bacteria, but not for Gram-positive bacteria, which is still an area of contention amongst researchers [45].”