Methylazoxymethanol acetate does not fully block cell genesis in the young and aged dentate gyrus

76 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus (2007, background): “Because suppression of adult neurogenesis after these manipulations is typically incomplet”
Epigenetic Modulation of Seizure-Induced Neurogenesis and Cognitive Decline (2007, background): “…correlates with impairment in some hippocampus-dependent learning tasks (Shors et al., 2001, 2002; Snyder et al., 2005), although the specificity of the above-mentioned ablation techniques (Monje et al., 2002) is subject to controversy within the field of adult neurogenesis (Dupret et al., 2005).”
Structural Plasticity and Hippocampal Function (2010, background): “One downside common to all of these methods is their nonspecific side effects that may complicate the interpretation of results (Dupret et al. 2005, Monje et al. 2003).”
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. (2009, result): “However, this strategy caused potentially severe side effects due to inhibition of cell proliferation in the whole animal, complicating the interpretation of the results (Dupret et al. 2005).”
Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory (2009, background): “Since MAM can induce cachexsia, we monitored the general health and weight of the injected mice [16].”