Neural network of cognitive emotion regulation — An ALE meta-analysis and MACM analysis

By Nils Kohn, Simon B. Eickhoff, M. Scheller, Angela R. Laird, Peter T. Fox, Ute Habel. NeuroImage, 2013

922 citations recorded by the source corpus.

Cognitive regulation of emotions is a fundamental prerequisite for intact social functioning which impacts on both well being and psychopathology. The neural underpinnings of this process have been studied intensively in recent years, without, however, a general consensus. We here quantitatively summarize the published literature on cognitive emotion regulation using activation likelihood estimation in fMRI and PET (23 studies/479 subjects). In addition, we assessed the particular functional contribution of identified regions and their interactions using quantitative functional inference and meta-analytic connectivity modeling, respectively. In doing so, we developed a model for the core brain network involved in emotion regulation of emotional reactivity. According to this, the superior temporal gyrus, angular gyrus and (pre) supplementary motor area should be involved in execution of regulation initiated by frontal areas. The dorsolateral prefrontal cortex may be related to regulation of cognitive processes such as attention, while the ventrolateral prefrontal cortex may not necessarily reflect the regulatory process per se, but signals salience and therefore the need to regulate. We also identified a cluster in the anterior middle cingulate cortex as a region, which is anatomically and functionally in an ideal position to influence behavior and subcortical structures related to affect generation. Hence this area may play a central, integrative role in emotion regulation. By focusing on regions commonly active across multiple studies, this proposed model should provide important a priori information for the assessment of dysregulated emotion regulation in psychiatric disorders.

Subfields: Cognitive Neuroscience, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/6d89a8cf74209e24782f226648907cfdd21810b4

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In Cognitive Neuroscience

In Experimental and Cognitive Psychology

Citations in the corpus

Putting Feelings Into Words: Affect Labeling as Implicit Emotion Regulation (2018, background): “In the neural domain, several meta-analyses of neural activations during reappraisal through reinterpretation each identified the following prefrontal regions often associated with cognitive control as more active during emotion regulation via reappraisal through reinterpretation: ventrolateral pref”
Behavior, Sensitivity, and power of activation likelihood estimation characterized by massive empirical simulation (2016, neutral): “Moreover, it may be discussed whether indeed something like “the” true location of an effect exists, given recent accounts of distributed coding and representation (Bzdok et al., 2015; Haxby, 2012; Kriegeskorte, 2009; Rissman and Wagner, 2012).”
Emotion Regulation: Current Status and Future Prospects (2015, positive): “Recent metaanalyses (Buhle et al., 2014; Diekhof, Geier, Falkai, & Gruber, 2011; Kalisch, 2009; Kohn et al., 2014) have yielded a fairly consistent set of findings.”