Clustered Pathway Genes in Aflatoxin Biosynthesis
By Jiujiang Yu†, P. Chang, K. Ehrlich, J. Cary, D. Bhatnagar, T. Cleveland, G. Payne, John E. Linz, C. Woloshuk, J. Bennett. Applied and Environmental Microbiology, 2004
808 citations recorded by the source corpus.
Aflatoxins, a group of polyketide-derived furanocoumarins (Fig. [1][1]), are the most toxic and carcinogenic compounds among the known mycotoxins. Among the at least 16 structurally related aflatoxins characterized, however, there are only four major aflatoxins, B1, B2, G1, and G2 (AFB1, AFG1, AFB2
Subfields: Plant Science
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Citations in the corpus
- Selection of Aspergillus flavus isolates for biological control of aflatoxins in corn (2011, background): “flavus, CPA is synthesized by proteins from a gene mini-cluster adjacent to the aflatoxin gene cluster on the right arm of chromosome 3 (Yu et al., 2004; Chang et al., 2009).”
- A reappraisal of fungi producing aflatoxins (2009, background): “The A. flavus and A. parasiticus aflatoxin gene clusters are about 70 kbp long, and consist of at least 24 different genes (Yu et al., 1995, 2004).”
- Ecology of Aspergillus flavus, regulation of aflatoxin production, and management strategies to reduce aflatoxin contamination of corn (2009, background): “This is followed by anthraquinones, xanthones, and ultimately aflatoxins synthesis (Bhatnagar et al., 2003, 2006a; Yabe, 2003; Yu et al., 2002, 2004).”
- Identification and quantification of mycotoxigenic fungi by PCR (2006, background): “However, clearly aflP and probably better aflQ, are not relevant to sterigmatocystin biosynthesis [31] and would be a valid choice for specific aflatoxin primers for food, etc.”
- Aflatoxins contamination in chilli samples from Pakistan (2007, methodology): “Paterson (2006) described a PCR method for the patulin biosynthetic pathway which appears to be specific for patulin producing fungi, and a similarly specific gene is required to be tested for aflatoxigenic fungi (e.g. aflQ (Yu et al., 2004).”
- Fungal secondary metabolism — from biochemistry to genomics (2005, neutral): “fcgi?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=9519"> Aspergillus parasiticus”