QUANTIFICATION AND SIGNIFICANCE OF PROTEIN OXIDATION IN BIOLOGICAL SAMPLES*

By E. Shacter. Drug metabolism reviews (Softcover ed.), 2000

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Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention (2003, background): “Proteins also undergo oxidation by several mechanisms [30,31].”
Chronic inflammation and cancer. (2002, background): “[49] Proteins[50] and lipids[51] are also significant targets for oxidative attack, and modification of these molecules can increase the risk of mutagenesis.”
Protein Oxidation: Basic Principles and Implications for Meat Quality (2013, background): “In addition, ROS can be generated by exposure of organisms to exogenous agents including ultraviolet (UV) light, irradiation (X-rays, γ -rays, ultraviolet A, and visible light in the presence of a sensitizer), chemical reagents (metal ions such as Fe2+ and Cu+, HONOO, ozone, N2O2, deoxyosones, ketoa”
Oxidative Stress and Antioxidant Defense (2012, background): “Gamma rays, metal-catalyzed oxidation, HOCl, and ozone can cause formation of carbonyl groups.(129)”
Oxidative modifications to cellular components in plants. (2007, background): “Tryptophan oxidation is another apparently irreversible protein modification (96).”