Evolution of Supergene Families Associated with Insecticide Resistance

By H. Ranson, C. Claudianos, F. Ortelli, C. Abgrall, J. Hemingway, M. Sharakhova, M. Unger, F. S. Collins, René Feyereisen. Science, 2002

651 citations recorded by the source corpus.

Subfields: Molecular Biology, Pharmacology, Plant Science

View Paper: https://www.semanticscholar.org/paper/6ad659eb538f51e39e6f8d83154b3b77a9d09f39

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Citations in the corpus

A deficit of detoxification enzymes: pesticide sensitivity and environmental response in the honeybee (2006, background): “…reconstruction of the radiation still invokes three single gene translocations to distant sites and just two of the classical adjacent, head-to-tail single gene duplications that predominate in the recent radiations of D. melanogaster and An. gambiae (Ranson et al., 2002; Oakeshott et al., 2005a).”
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. (2004, background): “It is possible to name the remaining genes and pseudogenes in other species, however, in order of their location; this positional naming has been done, for example, with most of the 105 mosquito (Anopheles gambiae) CYP genes [ 6 ].”
Molecular mechanisms of metabolic resistance to synthetic and natural xenobiotics. (2007, background): “In addition to conjugation and dehydrochlorination, GSTs are also involved in intracellular and circulatory transport of endogenous lipophilic compounds, xenobiotic binding, and sequestration.”
Estimating the tempo and mode of gene family evolution from comparative genomic data. (2005, background): “Researchers may now focus on large-scale genomic differences between organisms that play an important role in adaptive evolution, including large changes in the size of gene families (e.g., Tatusov et al. 1997; Lander et al. 2001; Snel et al. 2002; Lynch and Conery 2003).”
Genetic Polymorphism in Heterogeneous Environments: The Age of Genomics (2006, background): “The genetic basis of insecticide resistance may be the result of many genes (particularly in laboratory-selected strains), of mutants at a single or a few genes (ffrench-Constant et al. 2004, Oakeshott et al. 2003), or of expansion of gene families (Labbe et al. 2005, Ranson et al. 2002).”