Nucleotide excision repair and human syndromes.

By J. Boer, Jan H. J. Hoeijmakers. Carcinogenesis, 2000

706 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Oxidative DNA damage: mechanisms, mutation, and disease (2003, background): “Whereas polymorphisms in DNA repair genes generally produce subtle phenotypic differences between isoforms, defects in the NER pathways can have more profound effects as evidenced by xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy, the former condition at least being associated wit”
Chromosomal stability and the DNA double-stranded break connection (2001, background): “fcgi?cmd=Search&db=omim&term=xeroderma"> xeroderma pigmentosum , which is characterized by sun-sensitive skin and a predisposition to skin cance”
Telomeres and human disease: ageing, cancer and beyond (2005, background): “cgi?id=278760">xeroderma pigmentosum syndrome , which shows hypersensitivity to UV light, premature ageing and increased incidence of skin cance”
UV-induced skin damage. (2003, background): “Skin cancer after UV irradiation by DNA polymerase d and o. Finally, DNA ligase 1 might be carrying out the ligation of the repair patch (de Boer and Hoeijimakers, 2000).”