UV-induced skin damage.

By M. Ichihashi, M. Ueda, A. Budiyanto, T. Bito, M. Oka, M. Fukunaga, K. Tsuru, T. Horikawa. Toxicology, 2003

946 citations recorded by the source corpus.

Subfields: Cell Biology, Dermatology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/55e05a8fb24fc30c49c8077ca05039b43abdc418

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R. Varì
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Citations in the corpus

Oxidative Stress in Aging Human Skin (2015, background): “It is considered that a mutation in p53 leads to an inability of the cells to induce apoptosis, increasing the risk for a cancerous transformation [305,311].”
Flavonoids and Other Phenolic Compounds from Medicinal Plants for Pharmaceutical and Medical Aspects: An Overview (2018, background): “It induces extensive production of reactive oxygen species (ROS) and eventually causes skin damages [76].”
Skin photoprotection by natural polyphenols: Anti-inflammatory, anti-oxidant and DNA repair mechanisms (2009, background): “UVB radiation can induce both direct and indirect adverse biologic effects including the induction of oxidative stress, DNA damage, premature aging of the skin [13, 28 , 71], and multiple effects on the immune system [51, and reviewed in 64, 74], which together play important roles in the generatio”
Photoaging: mechanisms and repair. (2006, background): “UVB-induced DNA mutations occur by chemical change and include cyclobutane pyrimidine dimers and (6-4) photoproducts formed between adjacent pyrimidine bases (Fig 2).(57) Other DNA photoproducts have been reported, such Fig 1.”
Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. (2005, background): “Furthermore, ROS can be generated as a consequence of the intracellular metabolism of foreign compounds, toxins or drugs by cytochrome P450, monoxygenases, or because of exposure to environmental factors such as excessive iron salts or UV irradiation [4].”