Recruitment of HIV and Its Receptors to Dendritic Cell-T Cell Junctions

By D. McDonald, Li Wu, Stacy M Bohks, V. KewalRamani, D. Unutmaz, T. Hope. Science, 2003

752 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/66b47a4a066b8cc3a9bf3c20903d48c9b5036c88

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Citations in the corpus

HIV: cell binding and entry. (2012, background): “Second, it may bring the virus to a membrane region that has higher levels of coreceptor or important downstream signaling molecules (McDonald et al. 2003).”
T-cell-antigen recognition and the immunological synapse (2003, background): “, and it is tempting to speculate that such a mechanism provides T-cell specificity to antigen-presenting mature DC”
Dendritic-cell interactions with HIV: infection and viral dissemination (2006, background): “One reported route for viral transfer is across the ' infectious synapse ' (also known as the virological synapse), which is formed between DCs and T cell”
Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission (2008, background): “Such effective intercellular transfer of HIV-1 could occur through virological synapse”
The protein network of HIV budding. (2003, methodology): “(e.g., see Igakura et al., 2003; McDonald et al., 2003) GST fusion proteins were purified by glutathione affinity chromatography, cleaved to remove glutathione, and repurified by conven-and because the primary sites of virus release likely tional chromatography (Pornillos et al., 2002a).”
HIV-1 Cell to Cell Transfer across an Env-induced, Actin-dependent Synapse (2004, background): “Virus budding polarizes on infected cells, and the polar cap of viral egress is frequently directed toward the site of contact with the target cell (1, 3, 11).”
Virus Entry: Open Sesame (2006, neutral): “This virus can be regurgitated when dendritic cells interact with CD4-positive T cells and is able to infect the T cell in trans through infectious or virological synapses—a process that mimics the normal course of antigen presentation (McDonald et al., 2003).”
Avoiding the void: cell-to-cell spread of human viruses (2008, background): “DCs can spread HIV-1 to T cells after DC infection with HIV-1 or after short-term DC 'pulsing', during which the virus seems to be 'archived' prior to DC encounter of the T cel”
DC-SIGN: escape mechanism for pathogens (2003, background): “cgi?l=3683">LFA1 ), to facilitate transmission to T cell”