An iron delivery pathway mediated by a lipocalin.

By Jun Yang, D. Goetz, Jau-yi Li, Wenge Wang, K. Mori, Daria Setlik, T. Du, H. Erdjument‐Bromage, Paul Tempst, R. Strong and 1 more. Molecules and Cells, 2002

650 citations recorded by the source corpus.

Subfields: Hematology, Molecular Biology, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/656c1deaf476d0ba064206d407ecb74cde16e726

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Hematology

1. N. Borregaard

In Molecular Biology

1. Shintaro Sato
2. Alan Aderem
3. P. Devarajan
4. N. Borregaard
5. Shizuo Akira
6. Taro Kawai

In Nutrition and Dietetics

1. N. Borregaard

Citations in the corpus

• Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron (2004, background): “The expression of lipocalin 2 in multiple tissues outside the setting of infection suggests that it may have other functions, such as have been postulated in kidney developmen”
• The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. (2002, background): “Recently, 24p3 has also been implicated in processes asSummary diverse as apoptosis (Devireddy et al., 2001) and kidney cell differentiation (Yang et al., 2002 [this issue of Molec-First identified as a neutrophil granule component, ular Cell]).”
• Dual action of neutrophil gelatinase-associated lipocalin. (2007, methodology): “The importance of the peripheral compartment is illustrated by the fact that removal of these cells abolishes NGAL activity (9) but does not negate the actions of other epithelial inducers (11).”
• Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. (2005, background): “The protein is called neutrophil gelatinase–associated lipocalin (Ngal) or lipocalin 2 (39), a member of the lipocalin”
• Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. (2003, methodology): “conversion of mesenchymal cells into kidney epithelia (21).”