Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury.
By J. Mishra, Q. Ma, A. Prada, M. Mitsnefes, K. Zahedi, Jun Yang, J. Barasch, P. Devarajan. Journal of the American Society of Nephrology, 2003
1,757 citations recorded by the source corpus.
Subfields: Nephrology, Pathology and Forensic Medicine
View Paper: https://www.semanticscholar.org/paper/1b79490f3b25bcfd7e853dae55f87f14ef5e7b27
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In Nephrology
- Claudio Ronco
- K. Makris
- P. Devarajan
- V. Vaidya
- R. Bellomo
- C. Edelstein
- Joseph V. Bonventre
- John A. Kellum
Citations in the corpus
- Urinary kidney injury molecule-1: a sensitive quantitative biomarker for early detection of kidney tubular injury. (2006, background): “An ideal biomarker to detect AKI in animal studies should be organ and site specific, sensitive to detect minor perturbations in renal function, correlate with the degree of tubular injury, persist throughout the time course of renal injury to indicate progression and regression of injury, be noninv”
- Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. (2005, methodology): “To examine the functional significance of Ngal expression in renal ischemia, we first reproduced a common model of renal damage (44, 46) but used mice.”
- The Outcome of Neutrophil Gelatinase-Associated Lipocalin (NGAL)-positive Subclinical Acute Kidney Injury: A Multicenter Pooled Analysis of Prospective Studies (2011, background): “It was iscovered with unbiased transcriptomic approaches (8,9); it s rapidly induced and released from the injured distal ephron in experimental models and human disease 5,9,10); its urine and plasma concentrations increase proortionally to severity and duration of renal injury (9,11,12); ts concent”
- Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. (2009, background): “Setting & Population: Different clinical settings of AKI.”
- Urinary IL-18 is an early predictive biomarker of acute kidney injury after cardiac surgery. (2006, background): “NGAL protein was also markedly induced in kidney tubule cells early after ischemia in mouse models.(18) Importantly, NGAL protein was easily detected in the urine very early after ischemic injury in animals.”