Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier

By Jason D. Huber, R. Egleton, T. P. Davis. Trends in Neurosciences, 2001

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Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions (2006, positive): “TJ proteins undergo rapid changes in expression, subcellular redistribution, and posttranslational modifications, which in turn affect protein–protein interactions (Huber et al. 2001; Feldman et al. 2005).”
Modelling of the blood–brain barrier in drug discovery and development (2007, neutral): “A number of cytoplasmic accessory proteins, including zonula occludens protein 1 ( ZO-1 ), ZO-2 and cingulin , link the transmembrane proteins to the actin cytoskeleton allowing paracellular transport to be modulated in response to different stimul”
Innate immunity: the missing link in neuroprotection and neurodegeneration? (2002, neutral): “Perturbations in the stability of the BBB have been reported in disease states such as Alzheimer's disease, stroke and HIV encephaliti”
Three or more routes for leukocyte migration into the central nervous system (2003, positive): “These unique features of the capillary endothelium that exclude serum proteins and tracer molecules from the CNS are collectively known as the BB”
Tight junctions of the blood-brain barrier: development, composition and regulation. (2002, neutral): “The features of these molecules and their role in barrier formation are reviewed in detail elsewhere (Rubin and Staddon, 1999; Kniesel and Wolburg, 2000; Balda and Matter, 2000; Tsukita et al., 2001; Huber et al., 2001).”