The need to feed: homeostatic and hedonic control of eating.

By Clifford B. Saper, T. Chou, J. Elmquist. Neuron, 2002

1,130 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/61e66a5d4c372b8b7c0290256907356730bccd00

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

1. E. Maratos-Flier
2. J. Armstrong
3. Andrew D. Lawrence
4. S. Waddell
5. Joseph E LeDoux
6. J. Takahashi
7. U. Albrecht
8. John D. Beaver

In Endocrine and Autonomic Systems

1. Bryan L. Roth
2. J. Takahashi
3. Kent C. Berridge
4. J. Bass
5. U. Albrecht
6. Joseph E LeDoux
7. S. Waddell
8. C. Ye

In Nutrition and Dietetics

1. Joseph E LeDoux
2. U. Albrecht
3. Bryan L. Roth
4. P. Kenny
5. A. Kelley
6. Stephen R. Bloom
7. Bradford B. Lowell

Citations in the corpus

• Timing to perfection: the biology of central and peripheral circadian clocks. (2012, background): “In contrast, activation of leptin receptors in NPY/AgRP neurons inhibits the activity of the proappetite NPY/AgRP neurons (Saper et al., 2002), reinforcing the suppression of food intake and opposing the effects of ghrelin (see above).”
• Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High-Fat Diet (2011, background): “The highly palatable diet with varied flavors and textures seems to have disabled the normal homeostatic mechanism for energy balance possibly by activating the reward system (32).”
• Rapid, reversible activation of AgRP neurons drives feeding behavior in mice. (2011, background): “Through neuroscience research, critical contributions can be made in developing an understanding of the mechanisms underlying this problem, ultimately leading to treatment of this escalating disorder (1).”
• RETHINKING THE EMOTIONAL BRAIN (2012, positive): “…et al., 2007), reproduction (e.g., Pfaff, 1999; Oomura et al., 1988; Blaustein, 2008), thermoregulation (Nakamura and Morrison, 2007), fluid balance (Johnson, 2007; Fitzsimons, 1979), and energy/nutritional regulation (Elmquist et al., 2005; Morton et al., 2006; Saper et al., 2002) is strong.”
• Inhibition of food intake in obese subjects by peptide YY3-36. (2003, neutral): “Gut hormone PYY(3-36) physiologically inhibits food intake.”
• Gut Hormone Profiles Following Bariatric Surgery Favor an Anorectic State, Facilitate Weight Loss, and Improve Metabolic Parameters (2006, background): “Established actions of PYY include reduced gastric emptying, delayed gastrointestinal transit,(36) reduced food intake,(19,20) and may be a major factor influencing postprandial satiety.(15,37) All of these actions could be considered an appropriate response to acute small intestinal disease or shor”
• Individual Differences in Reward Drive Predict Neural Responses to Images of Food (2006, background): “However, food selection and intake are also powerfully influenced by the rewarding properties of individual items, such as their taste, smell, and sight (Toates, 1981; Berridge, 1996; Saper et al., 2002).”
• Behavioural indicators of hunger in dairy calves (2008, background): “Therefore, hunger is not only related to a lack of nutrients but can be influenced by a host of internal and external factors including neural pathways that are still not well understood (Saper et al., 2002).”